Exam 1 – Lecture 7: Connective Tissue 1 Flashcards
What happens in lateral domains?
Cell to cell adhesions/communications
What are tight juctions?
Occluding junction
Intercellular barrier
What are the 3 portions of tight junctions?
Zonula occludens
Zonula adherens
Macula adherens
What portions of the tight junctions are the anchoring junctions?
Zonula adherens
Macula adherens
What is the zonula occludence?
The most apical portion of tight junctions which is the barrier for fluid
What is the macula adherens portion of tight junctions?
The portion that tightly connects the tight junction
Desmosome
What are examples of different cell adhesion molecules?
Cadherins
Integrins
Selectins
Immunoglobulin superfamily
What are cell adhesion molecules?
Markers on the surface of the cells
What do selectins do?
Help cells migrate from tissue and identify different things
What do gap junctions do?
Help cell communicate
What is a type of gap junction?
Nexus
What is the basal domain?
Attachment to basement membrane
What happens in the basal domain?
Cell-matrix interaction
What is the basal lamina made of?
Collagens
Laminin
Proteoglycans
What does a hemidesmosome do?
Helps with attachment to the underlying basement membrane
What are the 2 types of glands?
Endocrine and exocrine
What do endocrine glands do?
Release products directly into the blood stream
What do exocrine glands do?
Release their product into some other lumen/space
What do glands secrete?
Merocrine
Apocrine
Holocrine
What is merocrine?
Membrane bound vesicles
Where is aprocine?
Apical with cytoplasm
What do holocrines do?
Apoptosis, whole cell
What are glands lined with?
Epithelium
What are glands characterized by?
If they are mucous or serous
What do mucous glands release?
A lot of proteoglycans
What do serous glands release?
Primarily water
What is connective tissue named for?
Matrix
What are 3 examples of types of connective tissue?
Fibrous
Cartilage
Bone
What are the different fiber types that make up connective tissue?
Collagen
Reticular
Elastic
What is the most abundant protein in a mammal’s body?
Collagen
What is collagen made of?
Fibrils
What is the structure of collagen?
Triple helix
What are the polymers of collagen?
Fibrillar Fibril associated Hexagonal network Transmembrane Multiplexins
What is collagen made by?
Fibroblasts
What is collagen used for?
To give strength to a tissue