Exam 1 – Lecture 9: Cartilage Flashcards
What does cartilage provide?
Protection
What is cartilage used as?
Modeling for bone
What are the 3 types of cartilage?
Hyaline
Elastic
Fibrocartilage
Why does cartilage heal poorly?
It does not have blood vessels
What kind of matrix is in the hyaline cartilage?
Homogenous amorphous
What are 3 major compounds in matrix of hyaline cartilage?
Collagen
Proteoglycans
Mutliadhesive glycoproteins
What proteoglycans are found in the matrix of hyaline cartilage?
Hyaluronan
Chondroitin sulfate
Keratan sulfate
What is the most common type of cartilage?
Hyaline
What do proteoglycans provide?
Structure to cartilage
What is hyaline cartilage the model for?
Developing bone
What is hyaline cartilage made of?
Dense connective tissue
What is hyaline cartilage involved with?
Embryologic development
Fracture repair
What are locations of elastic cartilage?
External ear
Auditory tubes
Epiglottis
What is fibrocartilage a combination with?
Dense connective tissue
What is fibrocartilage made of?
Type 1 and 2 collagen
What does fibrocartilage do?
Reduce compressive and shearing forces
What are the locations of fibrocartilage?
IV disks
Pelvic symphysis
Articular disks meniscus
What are the 2 types of growth?
Appositional and interstitial
Describe appositional growth
Occurs at the surface
Grows down from perichondrium
Carried out by modified fibroblasts
Describe interstitial growth
Occurs centrally
Grows down from existing chondrocytes
How does cartilage repair happen?
Calcification
What are osteoclasts?
Cells that reabsorb bone because bones are constantly being torn down and rebuilt
What type of collagen is the mineralized matrix of bone made of?
Mostly type 1
What are the different possible shapes of bones?
Long
Short
Flat
Irregular
What are the 2 types of densities of bones?
Spongy
Compact
What does bone provide?
Rigid structure and protection
What is bone made of?
Lacunae connected by canaliculi
What is the development of bone called?
Osteogenesis
What lives within lacunae?
Osteocytes
What is the outside of the bone?
Periosteum
What lives on the periosteum?
Nerves
What is the inside of the bone?
Cavity endosteum
What is the cartilage of the bone known as?
Epiphysis
What is in a mature bone?
Osteon (Haversian system)
Blood supply
Less dense cellularity