Exam 1 – Lecture 10: Bone Flashcards
What is within an osteon?
Central canal Lamellae Lacunae Canaliculi Perforating canal
What do osteoblasts secrete?
Matrix type 1 collagen
What do osteoblasts do?
Calcification
Bone-lining
What are osteocytes?
Mature bone cell within lacuna
What does the lacuna of osteocytes do?
Sends out cell processes
What do osteoclasts do?
Bone resorption
Endocytotic absorption
What do osteoclasts contain?
Howslip’s (howship’s) lacuna
What kind of cells are osteoclasts?
Mononuclear hematopoeitic progenitor cells
What does the ruffled border of osteoclasts allow for?
Active
Hydrolases
Protons
What are the 2 types of bone formation?
Endochondral
Intramembranous
What goes through endochondral formation?
Long bones
Hyaline cartilage
Epiphyseal
What goes through intramembranous formation?
Flat bones
Mesenchymal
Subperiosteal
Spicules, trabeculae
What is bone remodeling and mineralization like?
Constant process that is cell-regulated/extracellular
What increases during bone remodeling and mineralization?
Parathyroid hormone
What causes bone remodeling and mineralization?
Calcitonin