Exam 1 – Lecture 10: Bone Flashcards
What is within an osteon?
Central canal Lamellae Lacunae Canaliculi Perforating canal
What do osteoblasts secrete?
Matrix type 1 collagen
What do osteoblasts do?
Calcification
Bone-lining
What are osteocytes?
Mature bone cell within lacuna
What does the lacuna of osteocytes do?
Sends out cell processes
What do osteoclasts do?
Bone resorption
Endocytotic absorption
What do osteoclasts contain?
Howslip’s (howship’s) lacuna
What kind of cells are osteoclasts?
Mononuclear hematopoeitic progenitor cells
What does the ruffled border of osteoclasts allow for?
Active
Hydrolases
Protons
What are the 2 types of bone formation?
Endochondral
Intramembranous
What goes through endochondral formation?
Long bones
Hyaline cartilage
Epiphyseal
What goes through intramembranous formation?
Flat bones
Mesenchymal
Subperiosteal
Spicules, trabeculae
What is bone remodeling and mineralization like?
Constant process that is cell-regulated/extracellular
What increases during bone remodeling and mineralization?
Parathyroid hormone
What causes bone remodeling and mineralization?
Calcitonin
What does adipose tissue do?
Energy homeostasis
What is most of what is stored in adipose tissue?
Triglycerides
What are the 2 forms of adipose tissue?
White and brown fat
What is white adipose tissue like?
Unilocular
One large cell
What is white adipose tissue used for?
Energy storage
Insulation
Cushion vital organs
Produce hormones
What does white adipose tissue line up in?
Panniculus
What is brown fat like?
Multilocular
What is brown fat used for?
Thermogenesis
Where is brown fat usually located?
In axilla, inguinal regions, and the base of the heart
What are osteoblasts like?
Cuboidal
Basophilic cytoplasm
Prominent golgi
Gap junctions
Why is the cytoplasm of osteoblasts basophilic?
There is so much nucleic acid that they are constantly laying downs ostioles to make protein
