Exam 3 – Lecture 20: Hemic-Lymphatic 1 Flashcards
What makes up the hemic-lymphatic system?
Blood
Lymphatic system
How much of body weight is made up by blood?
8%
What are the different types of blood?
Erythrocytes
Leukocytes
Platelets
What are the different types of leukocytes?
Granulocytes
Agranulocytes
What are the granulocytes?
Neutrophils
Eosinophils
Basophils
What are the agranulocytes?
Lymphocytes
Monocytes/macrophages
What percentage of blood is the cellular component? What is the majority of that?
35-45%
RBCs
What percentage of blood is the fluid compartment (plasma or serum)?
55-65%
Which can clot, serum or plasma? Why?
Serum
There is more protein in plasma than serum
Describe white blood cells
Leukocytes
Discrete cells
Mesodermal
Granulocytes vs agranulocytes
Do WBCs have tight attachments surrounding colonies?
No
Look at picture of platelet, lymphocyte, and neutrophil
Look at picture of platelet, lymphocyte, and neutrophil
Describe neutrophils
Discrete, 10-12 μ cells Have a lobed nucleus with "non-stain" granules Chemotaxis, amoeboid motility Variable amount of cytoplasm First responders (make pus) Associated with bacterial infections
Describe eosinophils
Discrete, 10-12 μ cells
Have a bi-lobed nucleus with “red” granules
Chemotaxis, amoeboid motility
Variable amount of cytoplasm
Associated with parasites and allergic reactions
Describe basophils
Extremely rare Discrete, 10-12 μ cells Lobed nucleus with basophilic granules Function is unclear Less than 1% of leukocytes
Describe lymphocytes
Discrete, 10-12 μ round cells
Large central nucleus
Minimal to moderate cytoplasm
Found in thymus or bursal
What do B cells make? What do they become?
Make immunoglobulins
Become factories for antibodies
Describe monocytes
Discrete 15-25 μ cells Large bean-shaped nucleus Moderate to abundant cytoplasm Professional phagocytes Associated with granulomas
Describe platelets
Discrete 3-5 μ cellular fragments
Anuclear
Derived from megakaryocytes
Bags of clotting factors
Describe the lymphatic system
Immune system
Widely distributed
Closely aligned with cardiovascular system and blood
Many cell type
How is the lymphatic system widely distributed?
Surface (mucosa) oriented
Internal surveillance
What do lymphatic vessels resemble?
Veins, but carry lymph
What do afferent lymphatic vessels do?
Lead to lymph nodes
What do efferent lymphatic vessels do?
Leave lymph nodes
When lymph reenters circulation, what does it go through?
Thoracic duct
Describe lymph nodes
Small, encapsulated organs
Along lymphatic vessels
What is the main job of lymph nodes?
Filter lymph
What do lymph nodes play a role in?
Phagocytosis/immune response
What do afferent lymph nodes come through?
Capsule
What do efferent lymph nodes exit through?
Hilus
What comes through the hilus of lymph nodes?
Blood
What is the medulla of lymph nodes formed by?
Cords and sinuses
What is the site of filtration in the lymph nodes?
Sinuses
What does the cortex of lymph nodes consist of?
Lymphatic nodules
What can be found in the cortex of lymph nodes?
APCs
What is trabeculae?
Adjacent sinus in lymph nodes
