endocrine system Flashcards
endocrine system impacts
reproduction, growth, tissue maintenance/repair and energy metabolism
major endocrine system organs
hypothalamus, pituitary, pineal, thyroid, parathyroid, thymus, liver, pancreas, adrenal glands, ovary, placenta, testes
two organs that have functions outside of endocrine system
hypothalamus, pancreas
hypothalamus
coordinates autonomic NS, governs endocrine system via pituitary gland
the hypothalamus directs maintenance activities for homeostasis including
hunger, thirst, body temp, sleep, emotional response
pancreas
secrete digestive enzymes into the small intestine for macronutrient break down
pancreas produces
insulin, glucagon
the endocrine system also regulates physiological actions that manage
eustress and distress
eustress
positive, desirable form of stress that
eustress source examples
exercise, working toward obtainable goal
distress
negative form of stress
distress source examples
excessive stress or forms which fail to improve well-being; anxiety, lack of sleep
eustress: ____ hormones
anabolic
distress: ____ hormones
catabolic
anabolic hormones increase (5)
neural efficiency
vascular compliance
O2 extraction
cardiac function
musculoskeletal integrity and function
catabolic hormones increase (5)
platelet adhesion
cortisol production
LDL and triglycerides
susceptibility to low grade inflammation
loss of protein-sparing mehanisms
hormones are released by ______ to direct the actions of other tissues via _____
endocrine glands, chemical messages
hormones fall into two categories
steroid, polypeptide
steroid hormones
cholesterol based compounds
steroid hormone functions
sexual development, reproduction, tissue synthesis, inflammation regulation and metabolism
examples of steroid hormones
cortisol, estrogen, testosterone
polypeptide hormones
chains of amino acids synthesized with endocrine cells that attach to membrane receptors on cells to activate secondary messenger systems
examples of polypeptide hormones
insulin and glucagon
hormones travel through ____ and are picked up by _____
blood, receptor cells on target tissues
the pituitary gland regulates ____ hormones
anabolic
example of anabolic hormone regulated by pituitary
growth hormone
anabolic hormone
stimulating protein synthesis and tissue growth
growth hormone
cell division and proliferation by facilitating protein synthesis
growth hormone protects ___ and limits _____ by mobilizing lipids for fuel during exercise and plays a role in recovery
glycogen, carbohydrate metabolism
heavy weightlifting and other forms of intense exercise ____ the release of growth hormones which functions as a stimulator of _______ activity and release from the liver
expedites, insulin-like growth factor-1
insulin-like growth factor-1
central signaling hormone for the promotion of muscle growth following resistance training
gonadal hormones
testosterone and estrogen
gonadal hormones are released from reproductive organs to help
regulate sex-specific characteristics and various protective elements
testosterone
anabolic hormone produced in men and women that stimulates the development of male secondary sexual characteristics (facial hair) and acts on gene expression for protein synthesis
men possess ____x the quantity of testosterone than women
10
estrogen
steroid hormone that promotes the development and maintenance of female secondary characteristics (breast tissue) and is integral to bone maintenance in men and women
men convert ____ into a form of estrogen (____)
testosterone, estradiol
men normal levels of testosterone
270-1010 ng/dL
women normal levels of testosterone
15-70 ng/dL
children normal levels of testosterone
2-20 ng/dL
carbs are metabolized into ____ to maintain blood sugar levels
glucose
_____ hormones regulate blood sugar levels to limit _____ and ____
pancreatic
hyperglycemia
hypoglycemia
hyperglycemia
high blood glucose levels
hypoglycemia
low blood sugar levels
with hypoglycemia, metabolic demands of the ___ and ___ cannot be met
brain, CNS
the pancreas has two main functions
the production of digestive enzymes to break down fat, carbs, proteins for absorption via the lining of the small intestine
regulation of blood sugar levels
glucagon
regulate blood glucose by stimulating glycogen breakdown in the liver to release free glucose into circulation to increase levels
insulin
regulates blood glucose control and tissue growth, allows blood to be pulled from bloodstream into tissues based on need
insulin dysfunction is associated with
insulin resistance, diabetes
thyroid manages
metabolism via hormones T3 and T4
thyroid
gland, primary regulator for growth and the rate of metabolism within the body
thyroid function is important for
child development, lean mass maintenance
individuals suffering from “slow metabolism” may be actually experiencing
hypothyroidism
hypothyroidism
abnormally low activity of the thyroid which usually results in weight gain and can retard growth as well as mental development
the adrenal glands are located
above the kidneys
the adrenal glands release hormones from
adrenal cortex and medulla
adrenal gland hormones relegate
stress, exercise
major adrenal hormones
cortisol, epinephrine, norepinephrine
cortisol
regulates metabolic/cardiovascular functions and helps manage BP
cortisol is released in response to
exercise stress and low blood glucose concentration
chronic elevation in cortisol is associated with
overtraining
epinephrine
conditions of stress to increase blood circulation, ventilation, carb metabolism to prepare muscles for exertion
norepinephrine
increase BP and blood glucose, affinity for different tissue receptors than epinephrine but facilitates similar response
catecholamines
potent neurotransmitters that help the body respond to stress or elicit fight or flight response
examples of catecholamines
dopamine, epinephrine, norepinephrine
mineralocorticoid (2)
aldosterone, corticosterone
glucocorticoids (2)
cortisol, cortisone
androgens (2)
estrogen, testosterone
catecholamines (2)
epinephrine, norepinephrine
peptides (2)
somatostatin, substance P
adrenal cortex hormones
mineralocorticoids, glucocorticoids, androgens
adrenal medulla hormones
catecholamines, peptides
fight or flight response
acute increase in adrenal hormone activity which expedites enhancements in cardiac output, blood flow, and energy metabolism to rapidly deal with perceived stress/threat
the adrenals are very important to managing
exercise-based stress responses
anterior pituitary hormone, action
growth hormone; stimulate IGF, protein synthesis, growth, metabolism
thyroid hormone, action
thyroxine; stimulate metabolic rate, regulate cell growth and activity
adrenal cortex hormones (2) and actions
cortisol, aldosterone;
promote use of fatty acids and protein catabolism, conserve sugar, maintain blood glucose level; promote sodium, postasium metabolism and water retention
adrenal medulla hormones (2) and actions
epinephrine, norepinephrine;
increase cardiac output, increase glycogen catabolism and fatty acid release
has properties of epinephrine and constricts blood vessels
pancreas hormones (2) and actions
insulin, glucagon;
promote glucose uptake by the cell, stores glycogen, aids in protein synthesis
releases sugar from the liver into circulation
liver hormone, action
insulin-like growth factors
increase protein synthesis
ovaries hormone, action
estrogen
stimulate bone remodeling activity, female sex hormone
testes hormone, action
testosterone
stimulate growth, increase protein anabolism, reduce body fat, male sex hormone
resistance training (increases or decreases):
1. growth hormone
2. thyroxine and triodothyronine
3. insulin
4. IGF
5. cortisol
6. epinephrine
7. testosterone
increase
increase
decrease
increase
increase in heavy exercise
increase in heavy exercise
increase
high intensity training (above lactate threshold) ____ GH release
increases
testosterone is ____ during high-intensity aerobic activities
suppressed
insulin sensitivity is ____ and glucagon levels ____with prolonged exercise
heightened, increase
catecholamines ____ during steady state work
remain stable
cortisol activity ____ with prolonged duration
increases
aerobic work does not stimulate ____ pathways for hypertrophy as seen during weightlifting
GH-IGF
resistance training and endurance training at high intensities promotes the release of
various anabolic/adrenal hormones
long-duration, lower-intensity aerobic training suppresses ____ hormones while increasing potentially _____ hormones to supply energy
anabolic, catabolic stress
insulin sensitivity and consequence glucose management can be improved with
both forms of exercise
_____ training should be the staple of pre-diabetic programs
resistance
Which of the following directs functions such as hunger, thirst, temperature regulation and sleep?
a. Ovaries
b. Pancreas
c. Liver
d. Hypothalamus
d
The __________ secretes digestive enzymes and also produces hormones for blood glucose management.
a. Gallbladder
b. Testes
c. Adrenal glands
d. Pancreas
d
Which of the following is released from the liver and considered to be a primary signaling hormone for the promotion of muscle hypertrophy?
a. Thyroxine
b. Insulin-like growth factor-1
c. Estrogen
d. Testosterone
b
Which of the following has the greatest impact on one’s rate of metabolism?
a. Pineal gland
b. Adrenal gland
c. Thyroid gland
d. Pituitary gland
c
true or false: cortisol levels are reduced with regular bouts of long-duration endurance training
false
true or false: males and females produce estrogen for the promotion and maintenance of bone tissue
true
true or false: GH promotes anabolic activity, protein synthesis, and carbohydrate sparing in response to stressful exercise
true
___ functions to help regulate blood glucose levels by stimulating glycogen breakdown in the liver
glucagon
___ is suppressed during high-intensity aerobic activity but increased with resistance training
testosterone
identity the primary functions for each of the following adrenal hormones
a. cortisol
b. epinephrine
a. regulate numerous metabolic/cardiovascular functions and helps manage BP; released in response to exercise stress and low blood glucose concentrations to liberate energy
b. increases blood circulation, ventilation and carb metabolism to prepare muscles for exertion in response to perceived stress
identify at least two physiological impacts of eustress caused by hormonal responses
improved neural efficiency
vascular function
oxygen extraction
cardiac function
musculoskeletal function
identify at least two physiological impacts of distress caused by hormonal responses
increased platelet adhesion
cortisol production
blood LDL and triglyceride levels and susceptibility to low-grade inflammation
loos of protein-sparing metabolism
identify at least 5 organs or glands included in the endocrine system
Hypothalamus
pituitary gland
pineal gland
thyroid gland
liver
pancreas
ovaries
testes
adrenal glands
placenta (during pregnancy)