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Board Review - B - Systems Pharmacology > Endocrine II > Flashcards

Endocrine II Flashcards

1
Q

propylthiouracil

A

block thyroid peroxidase - inhibit iodine coupling

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2
Q

methimazole

A

block thyroid peroxidase - inhibit iodine coupling

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3
Q

tx hyperthyroid pregnant

A

propylthiouracil

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4
Q

adverse methimazole

A

teratogen

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5
Q

adverse propylthiouracil

A

hepatotoxic

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6
Q

levothyroxine

A

T4

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7
Q

triiodothyronine

A

T3

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8
Q

adverse T4 and T3

A

tachy
heat intolerance
tremor
arrhythmia

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9
Q

conivaptan

A

ADH antagonist

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10
Q

tolvaptan

A

ADH antagonist

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11
Q

tx central DI

A

desmopressin acetate

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12
Q

tx turner syndrome

A

GH

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13
Q

oxytocin

A

stimulate labor, uterine contraction, milk letdown

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14
Q

octreotide

A

somatostatin

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15
Q

demeclocycline

A

ADH antagonist

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16
Q

beclomethasone

A

glucocorticoid

17
Q

dexamethasone

A

glucocorticoid

18
Q

fludrocortisone

A

glucocorticoid

19
Q

hydrocortisone

A

glucocorticoid

20
Q

methylprednisolone

A

glucocorticoid

21
Q

triamcinolone

A

glucocorticoid

22
Q

mechanism glucocorticoid

A

metabolic
catabolic
anti-inflammatory
immunosuppressive

inhibit - NF-kB and phospholipase A2

23
Q

adverse glucocorticoid

A

iatrogenic cushings

peptic ulcer
steroid diabetes
steroid psychosis

24
Q

adverse stop glucocorticoid

A

adrenal insufficiency

25
Q

cinacalcet

A

sensitize Ca-sensing receptor in PTH
-decreased levels of PTH

tx of hyperCa due to primary or secondary hyperPTH

Board Review - B - Systems Pharmacology (26 decks)

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