Embryology of the CVS 2 Flashcards
what are the 2 ways in which blood vessels develop?
vasculogenesis
angiogenesis
what is vasculogenesis?
it is the process of blood vessel formation occurring a de novo production of endothelial cells
what is vasculogenesis defined as?
the new formation of a primitive vascular network
what is angiogenesis defined as?
the growth of new vessels from pre-existing blood vessles
what can angiogenesis basically be described as ?
the development o new blood vessels
what is the aortic sac?
it is a dilated structure in the embryo
what is the aortic sac lined by?
endothelial cells
where is the aortic sac located?
just above the truncus arteriosus
describe the aortic sac?
it is the primordial vascular channel from which the aortic arches arise
what arises from the aortic sac?
the aortic arches
what are the parts to each primitive aorta?
ventral part - ventral aorta
dorsal part - dorsal aorta
what occurs after the fusion of the 2 endocardial tubes?
the 2 ventral aorta partially fuse to form the aortic sac
what is an extension of the truncus arteriosus of the primordial heart tube?
the formation of the aortic sac
when do the pharyngeal arch arteries develop?
during the 4th and 5th week
where are the pharyngeal arch arteries located?
they are ventral to the dorsal aorta and arise from the aortic sac
what are the pharyngeal arteries?
they are a serious of 6 paired embryological vascular structures
what do the pharyngeal arteries give rise to?
they give rise to the great arteries of the neck and head
what are the 3 branches of the aortic branches?
the brachiocephalic trunk
the left common carotid artery
the left subclavian artery
what are pharyngeal arteries called when they communicate with aortic branches?
aortic arches
what is the dorsal aorta?
it is a large embryonic artery
how is the dorsal aorta formed?
it is formed by the fusion of the caudal parts of the paired primordial aorta
what does the dorsal aorta become?
it becomes the descending aorta and median sacral artery
what is an aberrant subclavian artery?
it is a rare anatomical variant of the origin of the right or left subclavian artery
what is the most common congenital vascular anomaly of the aortic arch?
the aberrant subclavian artery - this particular abnormality
what is a double aortic arch?
it is a relatively rare congenital cardiovascular malformation
describe a double aortic arch
it is an anomaly of the aortic arch in which 2 aortic arches form a complete vascular ring that can compress the trachea and/or oesophagus
what is patent ductus arteriosus?
it is a condition wherein the ductus arteriosus fails to close after birth
what is the ductus arteriosus?
it is a foetal blood vessel that closes soon after birth
what is coarctation of the aorta?
it is a congenital condition
describe coarctation of the aorta
narrowing of the aorta
where does coarctation of the aorta usually occur?
it usually occurs in the area where the ductus arteriosus inserts
what does coarctation of the aorta affect?
this narrowing of the aorta affects blood flow where the arteries branch out to carry blood along separate vessels to the upper and lower parts of the body
what does coarctation of the aorta cause?
it can cause high blood pressure or heart damage
what does placental circulation allow?
it allows the umbilical arteries to carry deoxygenated and nutrient-depleted foetal blood from the foetus to the villous core foetal vessels
what does vitelline circulation refer to?
it refers to the system of blood flowing from the embryo to the yolk sac and back again
where is the yolk sac situated?
it is situated on the ventral aspect of the embryo
what is the yolk sac lined by?
it is lined by endoderm, outside of which is a layer of mesoderm