ACS & AMI Flashcards

1
Q

what does an acute MI result from?

A

lack of oxygen supply to the working myocardium

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2
Q

what regional infarcts due to?

A

lack of blood flow occurring when an epicardial artery is blocked by atheroma or thrombus, or other obstructions

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3
Q

when does a heart attack occur?

A

a heart attack occurs when the flow of blood to the heart is blocked

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4
Q

how is the flow of blood to the heart most often blocked?

A

by a build-up of fat, cholesterol and other substances, which form a plaque in the arteries that feed the heart

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5
Q

what can the interrupted blood flow result in?

A

damage or destroying of the heart muscle

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6
Q

how many cases of MI occur annually approximately?

A

1.5 million

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7
Q

what are the MI characteristic ECG changes?

A

large peaked T waves
ST elevation
negative T waves
pathologic Q waves develop

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8
Q

how is a diagnosis of MI created?

A

by integrating the history of the presenting illness and physical examination with ECG findings and cardiac markers

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9
Q

what does a coronary angiogram allow?

A

visualisation of narrowing or obstructions on the heart vessels, and therapeutic measures can follow immediately

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10
Q

state 3 manifestations which ischaemic complications of MI can lead to

A

angina
reinfarction
infarct extension

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11
Q

state 5 manifestations mechanical complications of Mi can lead to

A
heart failure
cardiogenic shock
mitral valve dysfunction
aneurysms
cardiac rupture
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12
Q

state 4 manifestations arrhythmic complications of MI can lead to

A

atrial arrhythmias
ventricular arrhythmias
sinus node dysfunction
atrioventricular node dysfunction

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13
Q

what is thrombolytic therapy?

A

it is the use of drugs that dissolve blood clots basically

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14
Q

what is the major side effect of thrombolytic therapy?

A

bleeding

haemorrhage

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15
Q

what is the function of thrombolytic drugs?

A

they dissolve clots quickly

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16
Q

how do thrombolytics help?

A

they help to restart blood flow to heart and help to prevent damage to the heart muscle

17
Q

describe aspirin therapy of MI

A

aspirin therapy reduces the clumping action of platelets - possibly preventing a heart attack, aspirin interferes with your blood’s clotting action

18
Q

when can aspirin be used as acute therapy

A

following:
acute coronary syndrome
thrombotic stroke
Kawasaki’s disease

19
Q

what does aspirin decrease

A

mortality and recurrence of cardiovascular events

20
Q

what are the diagnostic methods of MI

A

electrocardiograms
blood tests
coronary angiography

21
Q

what is the treatment of MI

A

percutaneous coronary intervention

thrombolysis

22
Q

state the medication for MI

A

aspirin
nitroglycerin
heparin

23
Q

what is the use of low dose aspirin

A

it is a blood thinning medicine and prevents the formation of blood clots

24
Q

what does low dose aspirin help prevent?

A

heart attacks and strokes in people at high risk of them

25
Q

what is a weakness of low dose aspirin?

A

some people have serious side effects after taking low dose aspirin

26
Q

what are side effects of low dose aspirin

A
red, blistered and peeling skin
coughing up of blood
blood in your urine, faeces or vomit
yellow skin or eyes
painful joints in the hands
27
Q

state the role of beta blockers in the prevention of angina

A

they tend to decrease cardiovascular events

28
Q

what are ACE inhibitors used for?

A

secondary prevention of MI

29
Q

what do ACE inhibitors do?

A

they prevent the formation of the active peptide, angiotensin II, therefore, they reduce cardiac preload and after load without causing reflex tachycardia