Dopamine

Question 1

Class of Dopamine

Answer 1

Adrenergic, Vasopressor, Inotropic Agent

Question 2

MOA of Dopamine

Answer 2

Produces positive inotropic & Chronotropic effects. Constricts systemic vasculature increasing BP & preload. Increases myocardial contractility & stroke volume.

Question 3

Indications for Dopamine

Answer 3

Cardiogenic & septic shock. Hypotension w/low cardiac output states, distributive shock, second-line drug for symptomatic bradycardia.

Question 4

Contraindications for Dopamine

Answer 4

Hypersensitivity, Hypovolemic shock, pheochromocytoma, tachydysrhythmias, VF. Decrease dose to 1/10th for pts taking MAOI’s.

Question 5

Adverse reactions for Dopamine

Answer 5

Anxiety, AMI, chest pain, dyspnea, Ischemia, Palpitations, Increases Myocardial oxygen demand, tachydysrhythmias, HA, HTN, NV, TF, VT.

Question 6

Special Note for Dopamine

Answer 6

Dopamine is ALWAYS given as an IV drip

Mix 400mg in 250ml of D5W & run at appropriate rate

Question 7

Dosage of Dopamine for Adults

Answer 7

Doses greater than 20mcg/mg/min. Alpha effect predominate & may compromise circulation in the limbs.

Adult Renal Dose: 2-5mcg/kg/min IV/IO

Adult Cardiac Dose: 5-10mg/kg/min IV/IO

Adult Pressor Dose: 10-20mcg/kg/min IVO

Question 8

Dosage of Dopamine for Peds

Answer 8

IV/IO infusion at 5-20mcg/kg/min SLOWLY titrated to pt response.

Question 9

Duration of Action for Dopamine

Answer 9

Onset: 1-4 mins

Peak: 5-10 mins

Duration: Effects cease almost immediately after infusion is DC’d.