Diazepam

Question 1

Class of Diazepam (Valium)

Answer 1

Benzodiazepine, long-acting, sedative-hypnotic, anticonvulsant, Schedule IV drug.

Question 2

MOA of Diazepam (Valium)

Answer 2

Potentiate, effects of inhibitory neurotransmitters, raises the seizure threshold. Induces amnesia & sedation.

Question 3

Indications for Diazepam (Valium)

Answer 3

anxiety & agitation, alcohol withdrawal, cocaine OD, muscle relaxant, chemical restraint. Status Epilepticus, sedation for medical procedures (intubation, vent pts, Cardioversion),

Question 4

Contraindications of Diazepam (Valium)

Answer 4

Low BP, Coma, Hypersensitivity, Head Injury, acute narrow-angle glaucoma, Myasthenia Gravis, respiratory depression.

Bob Can’t Help His NAGging My Growing Rate of Depression.

Question 5

Adverse Reactions of Diazepam (Valium)

Answer 5

Ataxia, Confusion, dizziness, drowsiness, Resp depression, HA, hypotension, N/V, tissue necrosis, venous irritation, phlebitis, tachycardia, thrombosis

Question 6

“Note” for Diazepam (Valium)

Answer 6

Note: OD may be revered with Flumazenil

Question 7

Dosage of Diazepam for adults for seizure

Answer 7

5mg IV, SLOWLY, over 5 mins. Or 10mg IM.

Question 8

Dosage of Diazepam for anxiety

Answer 8

2-10mg IV/IM

Question 9

Dosage of Diazepam for premedication for Cardioversion

Answer 9

5-15mg IV over 5-10mins prior to Cardioversion

Question 10

Dosage of Diazepam for PEDS seizure

Answer 10

0.05-0.1mg/kg IV SLOWLY or 0.1-0.2mg/kg IM

Question 11

Duration of Action of Diazepam

Answer 11

Onset: 2-5mins

Peak: 15-30 mins

Duration: 20-50 mins