DNA structure Flashcards

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1
Q

DNA is made up of 4 types of macromolecules

A

known as nucleic acid, polysaccharides, lipids, and protein.

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2
Q

DNA stands for..

A

deoxyribonucleic acid

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3
Q

DNA must be able to…

A
  1. carry genetic info for one generation to the next.
  2. be easily and accurately copied before cell division.
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4
Q

explain nucleotides

A

DNA molecule is made of building blocks known as nucleotides.

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5
Q

what does DNA nucleotide consist of. (and diagram)

A
  1. a 5-carbon sugar (deoxyribose)
  2. a phosphate group
  3. one of 4 possible nitrogenous bases
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6
Q

who analysed DNA to find its components?

A

Phoebus Levene. in 1929, he said that DNA consist of deoxyribose sugar, nitrogenous bases, and phosphorus.

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7
Q

2 types of nitrogenous bases.

A

pyrimidines: cytosine, thymine (1 ring)
purines: guanine and adenine (2 rings).

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8
Q

what are the 4 nucleotides link together by?

A

sugar and phosphate groups to form chains, which vary in length and sequence of the nitrogenous bases.
(sugar phosphate backbone)

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9
Q

what provides genetic code.

A

sequence of nitrogenous bases. and also decides production of protein.

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10
Q

what bases match and what are they called

A

adenine = thymine
guanine= cytosine
these are called complementary base pairs.

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11
Q

how is DNA charged, and what is helix.

A

DNA is negatively charged and two strands of DNA twist around each other to form a double helix.

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12
Q

DNA has an orientation based on the numbering of carbons in the sugar molecule which is

A

5’ (5 prime) end
3’ end

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13
Q

what binds to what, on a DNA structure

A

*phosphate on 5’ end binds on to 3’ on the DNA nucleotide in front of it

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14
Q

why is DNA called anti-parallel?

A

two strands of DNA are oriented in opposite directions.

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15
Q

what is length of DNA measured in?

A

base pairs bp

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16
Q

what are histones

A

since DNA molecules are extremely long, in order to fit into cells, they fold up as much as possible. so DNA is twisted into special proteins called histone and hep condense them, so it’s organized into chromosomes.

17
Q

2 bonds

A

nitrogenous bases are bonded by hydrogen bonds (weak)
nucleotide to nucleotide bonded by phosphodiester (strong)