Chapter 6: Treatment

Question 0

Alcoholics Anonymous
1. _______ for alcoholics
2.Holds that there is _________ for alcoholism
3. Appears to work for some drinkers; actual success rate is unknown though it is known that ______ of members drop out in the ____ year.
4. It is more appealing to which gender?
5.Does not appeal to many people for several reasons
6. People who stick with AA are those who:
a.
b.
c.
d.
e.

Answer 0

1. support group
2. no cure
3. 64%, 1st
4. men
5. a. have a high socioeconomic status
   b. are in a stable social situation
   c. are highly motivated to quit
   d. are between ages 40-45
   e. have spouses who help them with the treatment

Question 1

It should be noted that these characteristics are predictive of success no matter what _____ is or what ___ is being abused.
(AA stickers)

Answer 1

• treatment

- drug

Question 2

Pharmacotherapies 
1. Disulfiram (Antabuse )
2. Acamprosate( antagonist for?)
3. Naltrexone (receptor antagonist for?)
a. 
b.
c.

Answer 2

1.blocks the action of aldehyde dehydrogenase leads to build up of acetaldehyde in the body and makes the person feel sick. Stops drinkers drink because of how ill they will get.
2.antagonist for glutamate. suppresses glutamate activity which is hyperactive during withdrawal. This lessens the aversiveness of withdrawal lowering the motivation to take alcohol
3. opioid receptor antagonist
(blocks opiate systems )
a. reduces the normal level of intoxication
b. reduces craving in abstinent heavy drinkers
c.modestly effective in reducing relapse, but individual differences are pronounced

Question 3

Side effects of Naltrexone?

Answer 3

committing, diarrhea, somnolence

extended injection =nausea, depressed appetite, dizziness and some injection site pain..

Question 4

What are the two formulations of Naltrexone ?

Answer 4

• oral naltrexone

- extended-release injection- remains effective for about a month

Question 5

Tiapride ?

Answer 5

-D2 dopamine receptor blocker -in france

Question 6

Other examples of drugs that affect dopaminergic systems?

Answer 6

antipsychotic: clozapine, aripiprazole and olanzapine (very effective in those with schizophrenia and bipolar disorder)

Question 7

Other drugs?

Answer 7

anticonvulsants, like topiramate and valproic acid/divalproex