Capter 7: Neurophysiology Flashcards
0
Q
At high doses BARBs can also open _____ channel directly and can cause respiratory depression and death
A
Cl-
1
Q
Benzodiazepine and barbiturates at low doses and z-drugs are all _______ which means they bind at their own sites and amplify the effect of GABA at its receptor.
A
allosteric modulators
2
Q
BDZs and Z-drugs cannot do this: ?
A
their effect has an upper limit and thus they are safer drugs
3
Q
Some BDZs are - GABA a modulators aka _________. The three characteristics are?
A
- inverse agonist
- decrease ability of GABA’s to open the Cl-Channel
- can cause tension, anxiety and panic
- can cause seizures
4
Q
BDZs have abuse potential though ___ so than BARBs via effects on ___.
A
less, DA (dopamine )
