Chapter 15: Cholinergic Hallucinogens

Question 0

Ibotenic Acid: 
1. Effects in Humans: 
A. Phase 1 (3)
B. Phase 2
C. Phase 3

Answer 0

A. Pleasant excitement
-sense of increased agility, lightness and strength
-Macropsia: objects seem larger
B. Hallucinations 
C. Deep sleep

Question 1

Ibotenic Acid:

1. found in?
2. Primary active ingredient?

Answer 1

1. Amanita muscaria = red capped mushroom

2. ibotenic acid

Question 2

Ibotenic Acid:

1. Excretion?
2. Neurochemical basis of action?

Answer 2

1. unchanged completely…it can be recycled

2. acetylcholine receptor agonist

Question 3

Anticholinergic Hallucinogens: The drugs of Witches and Sorcerers:

1. blocks what receptors in the brain?
2. found in the plant family of?
3. Are there vivid visual effects?

Answer 3

1. muscarinic acetylcholine receptors
2. Potato
3. no vivid visual effects

Question 4

Anticholinergic Hallucinogens: The drugs of Witches and Sorcerers:
1. What are the most common effects? (4)

Answer 4

A. Anticholinergic syndrome (involuntary movements)
B. clouded consciousness
C. Impaired sensory perception
D. Impaired memory

Question 5

Anticholinergic Hallucinogens: The drugs of Witches and Sorcerers:
1. Primary sources?
A. Deadly Night Shade (Atropa Belladonna)
L> contents
L> effect

Answer 5

A. atropine = pupil dilator, induces feeling of flying

Question 6

Anticholinergic Hallucinogens: The drugs of Witches and Sorcerers: 
1. Primary sources
B. Mandrake
L> shape
L>contains?(3)
L> effects

Answer 6

B.man shaped, contains atropine, scopolamine (available as a antiemetic) and hyoscyamine
- hallucinogen, hypnotic

Question 7

Anticholinergic Hallucinogens: The drugs of Witches and Sorcerers: 
1. Primary sources?
C. Henbane
L> seeds? 
L> contains? (2)
L> effects

Answer 7

C.toxicity of its seeds, scopolamine (motion sickness treatment) and hyoscyamine
- hallucinations, dilated pupils, restlessness, flushed skin, convulsions, hyperpyrexia , ataxia, hypertension, tachycardia

Question 8

Anticholinergic Hallucinogens: The drugs of Witches and Sorcerers: 
1. Primary sources?
D. Datura
L> contains? (2)
L> effects 
L> Indians use it as?

Answer 8

D.Contains scopolamine and hyoscyamine,

• effects: agitation, disorientation and confusion,
• used as ritual of passage for Algonquin Indians