Chapter 6: Neuropharmacology Flashcards
0
Q
The inhibitory activity of GABA a receptors is _______; this is responsible for the relaxation, drowsiness and loss of muscle control that ethanol induces.
A
-increased
1
Q
Does alcohol have one receptor site of action or many?
main ones? (2)
A
It has many systems that it affects at the same time and it can have different effects on different systems at different concentrations.
- GABA
- Glutamate
2
Q
Excitatory activity of glutamate (NMDA) receptors is ______; this is responsible for what deficits?
NMDA receptor up regulation (a compensatory response) contributes to ethanol ______ symptoms due to hyper-excitability of ______ pathways.
A
- decreased
- cognitive and memory
- withdrawal
- glutamatergic
3
Q
Dopamine release in the nucleus accumbens is what?
A
-increased