Chapter 6: Neuropharmacology Flashcards

0
Q

The inhibitory activity of GABA a receptors is _______; this is responsible for the relaxation, drowsiness and loss of muscle control that ethanol induces.

A

-increased

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1
Q

Does alcohol have one receptor site of action or many?

main ones? (2)

A

It has many systems that it affects at the same time and it can have different effects on different systems at different concentrations.

  • GABA
  • Glutamate
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2
Q

Excitatory activity of glutamate (NMDA) receptors is ______; this is responsible for what deficits?
NMDA receptor up regulation (a compensatory response) contributes to ethanol ______ symptoms due to hyper-excitability of ______ pathways.

A
  • decreased
  • cognitive and memory
  • withdrawal
  • glutamatergic
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3
Q

Dopamine release in the nucleus accumbens is what?

A

-increased

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