Chapter 6: Ethanol Elimination/excretion

Question 0

Over 90% of ethanol is ______ mostly in the liver. What’s not metabolized is excreted via ___.

Answer 0

metabolized

Question 1

A small amount of ethanol is vaporized in the lungs;therefore, what is reflected accurately in breath?

Answer 1

BAC

Question 2

The rate of metabolism is _____ and l_____, though it will vary among individuals. The mean is __mg/100 ml/hr with a range of - mg/100ml/hr.

Answer 2

constant,linear, 15, 10-20

Question 3

The first step in metabolism is ethanol being converted into _____ by the enzyme alcohol dehydrogenase aka the rate-limiting step. How much you metabolize depends on the amount of ____ you possess.

Answer 3

• acetaldehyde

- dehydrogenase

Question 4

The second step in metabolism : acetaldehyde is converted to ________ by aldehyde dehydrogenase .

Answer 4

acetyl-coenzyme A

Question 5

Though food slows absorption it does speed up the _____ of ethanol possibly by stimulating the ___.

Answer 5

metabolism, liver

Question 6

The secondary metabolizing system: microsomal ethanol-oxidizing system does: (2)

Answer 6

handles 5-10% of ethanol metabolism
chronic ethanol consumption increases microsomal enzymes that metabolize other drugs as well and is responsible for much of the tolerance and cross tolerance… (ex:barbiturates)