Chapter 6: Absorption of Ethanol

Question 0

First pass metabolism occurs in the stomach, does what to alcohol?

Answer 0

-alcohol in the stomach is exposed to high concentration of alcohol dehydrogenase the main enzyme that breaks down alcohol…

Question 1

Ethanol cannot be _____; ph of diluent has no effect on ___.

Answer 1

ionized, absorption

Question 2

Absorption is slowed by?? (3)

Answer 2

1. food : digestion process keeps food in the stomach for a set amount of time before moving on….slows down alcohol absorption
2. H2-receptor antagonists (ranitidine or zantac) reduce alcohol dehydrogenase levels. (alcohol will have an increased affect)
3. Gender: woman have less alcohol dehydrogenase in the stomach; higher BAC per unit

Question 3

Absorption is increased by? (3)

Answer 3

1. carbonation: expands stomach lining making it easier for things to pass through aka increases surface area
2. concentration (to a point) most rapid absorption occurs at about 80 proof (40% ethanol) (1/2% = proof aka proof = 2x%)
3. expectancy also plays a factor….those that expect to drink alcohol reached higher BAC than those that did not expect.