CH 23 Flashcards
Vessels and circulation; Veins and arteries
Systemic circulation
Consists of all blood vessels that extend to all body regions
Pulmonary circulation
Consists of blood vessels that take blood to and from the lungs for the purpose of gas exchange
Companion vessels
When an artery travels with a corresponding vein because they supply the same body region and tend to lie next to each other
Tunic
Layers of vein and artery wall
Tunics surround the ______
lumen: inside space of the vessel where blood flows
Tunics of blood vessels
- Tunica intima
- Tunica media
- Tunica externa
Tunica intima aka tunica interna
Innermost layer of blood vessel
Components of tunica intima
- Endothelium
- Subendothelial layer
- Internal elastic lamina*
- not in veins
Endothelium
Simple squamous ET that lines the blood vessel lumen
Subendothelial
Made of thin layer of areolar loose CT
Internal elastic lamina
Elastic CT typically only in arteries; separates the tunica intima and tunica media
Tunica media
Middle layer of vessel walls
Components of tunica media
- Smooth muscle
- External elastic lamina*
- not in veins
Vasoconstriction
Sympathetic innervation causes smooth muscle to contract
All arteries are capable of this, amount of vasoconstriction is regulated by proportion of smooth muscle to elastic fibers. More smooth muscle = greater vasoconstriction
Vasodilation
Sympathetic innervation causes smooth muscle cells to relax, dilate, or widen
External elastic lamina
Elastic CT, only in arteries
Tunica externa
Outermost layer of vessels that helps anchor the vessel to other vessels; separates the tunica media and tunica externa
Components of tunica externa
- Areolar CT that contains elastic and collagen fibers
- Vasa vasorum
Vasa vasorum
- Means “vessels of vessels”
- Network of small arteries in very large vessels to supply blood to tunica externa
Thickest wall layer in arteries
Tunica media
Thickest wall layer in veins
Tunica externa
Arteries become progressively (smaller/larger) as they branch and extend farther from the heart, as the veins become progressively (smaller/larger) as they unite and merge and come closer to the heart
smaller; larger
Veins vs. arteries
Arteries tend to have more collagen and elastic fibers in all their tunics, which means that artery walls tend to remain open/ patent, can spring back into shape, and can withstand changes in blood pressure
Vein walls tend to collapse if there is no blood in the vein
Capillaries only contain the _______
tunica intima
contains basement membrane and endothelium only
Lacks CT and muscle layers, allowing for rapid gas and nutrients exchange between blood and tissues
Arterioles
Smallest arteries
Have less than 6 layers of smooth muscle in tunica
Large arterioles have all 3 tunics, small arterioles have an endothelium surrounded by a single layer of smooth muscle cells
Veins
Drain capillaries into heart
Venules
Smallest veins that are companion vessels with arterioles; merge to form veins
Smallest venules
Postcapillary
Diapedesis
Mechanism by which leukocytes migrate from blood to interstitial fluid; occurs mainly in postcapillary venules
Capillary bed
Group of 10 to 100 capillaries (capillaries don’t operate independently)
Capillary beds are fed by ___________
metarterioles
Metarteriole
Cross between an arteriole and capillary (contains smooth muscle); vessel branch of arteriole
Thoroughfare channel
Distal part of metarteriole that contains no smooth muscle; continuous with all vessels
Thoroughfare channels carries blood (towards/away from) ________(vessel) and leads to __________
away from capillaries; venules
Postcapillary venule
Connects to a thoroughfare channel; drains capillary bed
True capillaries
Branch from metarteriole that makes up the bulk of a capillary bed; capillary that directly branches off metarteriole
Precapillary sphincter
Smooth muscle ring that controls blood flow into true capillaries; entrance to capillary
Relaxation of precapillary sphincter allows blood flow into true capillaries
Contraction reroutes blood from metarteriole to thoroughfare channel to postcapillary venule
Elastic arteries AKA conducting arteries
Largest arteries that conduct blood away from heart to smaller muscular arteries; Abundance of elastic fibers allow elastic artery to stretch when a heart ventricle ejects blood into vessels
Muscular arteries AKA distributing arteries
Medium-sized arteries that distribute blood to the body, organs, and tissue; elastic fibers are confined to 2 circumscribed rigns
Functional unit of cardiovascular system
Capillaries
What do capillaries connect?
Arterioles to venules
Types of capillaries
- Continuous
- Fenestrated
- Sinusoid
Systemic circulation steps
1) Oxygenated blood flows from the LA to the LV then is pumped into the aorta
2) Blood passes from aorta into elastic arteries to muscular arteries to arterioles
3) Blood in arterioles enters systemic capillaries for exchange of gases and nutrients
4) Deoxygenated blood exits capillary beds into venules and veins
5) Deoxygenated blood is conducted to either SVC or IVC and then enters RA
LA
LV
aorta
elastic arteries
muscular arteries
arterioles
systemic capillaries
capillary bed
venules and veins
SVC or IVC
RA
Pulmonary circulation steps
6) Blood flows from the RA to RV then is pumped to the pulmonary trunk
7) Pulmonary trunks conducts deoxygenated blood into pulmonary arteries to the lungs
8) Blood passes through smaller and smaller arteries before entering pulmonary capillaries for gas exchange
9) Oxygenated blood exits the lung via series of progressively larger veins that merge to form the pulmonary veins
10) Pulmonary veins drain in the LA
11) Cycle repeats
RA
RV
pulmonary trunk
pulmonary arteries
pulmonary veins
LA
Pulmonary circulation is responsible for carrying (deoxygenated/oxygenated) blood from the (left/right) of the heart to the lungs and returning newly oxygenated blood to the (left/right) side of the heart
deoxygenated; right; left
Arteries carry deoxygenated blood, veins carry oxygenated blood
Pulmonary circulation
Systemic circulation is responsible for carrying (deoxygenated/oxygenated) blood from the (left/right) side of the heart and returning (deoxygenated/oxygenated) blood back to the right side of the heart
oxygenated; left; oxygenated
Left side of heart is oxygenated
Arteries carry oxygenated blood, veins carry deoxygenated blood
Systemic circulation
Arteries and veins of the heart
Arteries:
- R/L coronary arteries
- Marginal artery
- Circumflex artery
- Anterior interventricular artery
- Posterior interventricular artery
Veins:
- Anterior cardiac vein
- Small cardiac vein
- Middle cardiac vein
- Great cardiac vein
- Coronary sinus
Coronary arteries
- Supplies wall of heart
- Travels in coronary sinus
- R/L
Only branch of ascending aorta
Coronary arteries
Oxygenated blood is pumped out of the LV of the heart and enters the _______
ascending aorta
The ascending aorta curves toward the left side of the heart and becomes the ________
aortic arch
Coronary sulcus AKA atrioventricular sulcus
Deep groove separating the atria and ventricles that extends the entire heart circumference
Branching of right coronary artery
- Right marginal artery
- Posterior interventricular artery
Right marginal artery
Branches of right coronary artery; supplies right ventricle
Posterior interventricular artery
Supplies posterior surface of heart of both left and right ventricles
Branching of left coronary artery
- Anterior interventricular artery
- Circumflex artery
Anterior interventricular artery
Branching of left coronary artery that supplies anterior surface of left and right ventricles and most of the interventricular septum
Circumflex artery
Supplies left atrium and ventricle
Anatomoses
Tiny connections of arteries; where 2 arteries or 2 veins converge to supply the same body part
Functional end arteries
Artery with tiny anatomoses that it can be considered an end artery
e.g. coronary artery
End artery
Artery with no anatomoses; providing only one pathway to which blood can reach an organ
e.g. renal and splenic artery
Venous return
Flood of blood from systemic circulation towards the right of the heart (flow of blood back to heart); occurs in cardiac veins
Great cardiac vein
Runs alongside anterior interventricular artery
Middle cardiac vein
Runs alongside posterior interventricular artery
Small cardiac vein
Travels close to the right marginal artery
Anterior cardiac veins
Drains small portion of anterior surface of ventricle into RA
Coronary veins
Carries blood away from tissue it travels through
Coronary sinus
Large vein in posterior aspect of coronary sulcus; Drains directly into RA of heart; Carries blood away from heart wall
Pulmonary circuit
- Pulmonary trunk
- R/L pulmonary arteries
- Pulmonary veins
Pulmonary trunk
Large artery that transports blood from RV into pulmonary circulation
Pulmonary artery
Branchings of pulmonary trunk that carry deoxygenated blood to lungs
Pulmonary veins
Where oxygenated blood travels to the LA
Aorta
Artery that conducts blood from LV to systemic circulation
3 branches of aorta off the aortic arch
- Brachiocephalic trunk
- Left common carotid artery
- Left subclavian artery
Bifurnicate
Branches off
Brachiocephalic trunk bifurnicates into
- Right common carotid artery
- Right subclavian artery