Cell Physiology Flashcards
What ia a molar solution ?
when 1 mole of a solute is dissolved in 1 L of solvent
What are nanolitres ?
1,000,000,000 times less than 1 L
What are microlitres ?
1,000,000 times less than 1 L
What are millilitres ?
1,000 times less than 1 L
What is a molal solution ?
a measure of concentration of a solute in a solution in terms of the amount of the amount of substance in a specified amount of solvent
What are the properties of water ?
polar and neutral
What does water do when ionic compounds are dissolved in it ?
the ionic compound dissociates into positive ions and negative ions
How many moles are present if one mole of NaCl dissociates ?
2 moles - 1 mole of sodium and 1 mole of chloride
How much of a human consists of water ?.
60%
How much of a human is roughly protein ?
17% protein
What can be used to estimate the fluid loss in babies with diarrhoea ?
1kg=1L
therefore the fluid loss can be estimated using the mass loss
What are the locations of water in the body ?
intracellular fluid
extracellular fluid
special spaces - eg.vitreous humour
What makes up extracellular fluid ?
25% is plasma
75% is interstitial fluid
How much of body water consists of extracellular fluid ?
one third
How much body water is made of intracellular fluid ?
two thirds
If the reference man is 70 kg how much Intracellular fluid does he have ?
70 kg - 60% is water - 42 kg
2/3 of water is intracellular - 28L
What do body fluids consist of ?
salts - anions and cations - these can be monovalent or polyvalent
organic compounds - eg.cholesterol - these are uncharged
proteins - these are different sizes and can be charged depending on the pH
Dissolved gases that are uncharged
What are the relative levels of sodium in/outside a cell ?
Sodium is high outside the cell in the extracellular fluid this allows for cells the become excited
What are the levels of potassium in/outside the cell ?
Potassium is always high in the cytoplasm - it is the reciprocal of sodium
What are the levels of calcium in/outside a cell ?
calcium is very low in the cytoplasm and higher outside the cell
It is bound inside the cells and is tightly regulated
What is the level of chloride ion in/outside the cell ?
Chloride is high in the extracellular fluid and low in the cytoplasm
it is responsible for inhibitory nerve cells
What is the function of HC03- ?
carbon dioxide , pH buffering in the blood
What is the role of the phosphate ion ?
ATP/nucleic acids - it is high in the cytoplasm
Where is movement of solutes across tissue/cellular membranes important ?
Salivary glands / secretion secretion of substances into the blood penetration of drugs into tissues gaseous exchange Membrane potential