c39 final Flashcards
1
Q
what is the main function of B cells
A
to produce antibodies
2
Q
where are antibodies present
A
in the blood, lymph, and extracellular fluids
where they bind to extracellular bacteria and viral particles
also found at mucosal surfaces
3
Q
how are B cells activated?
A
multiple surface B cell receptors bind to the same antigen and this causes B cell receptors (BCRs) to cluster together … this clustering and CROSS linking sending activation signals into the B cell
4
Q
antigen interactions with IgM-BCRs on a B cell surface bring multiple BCRs close together
A
cross linking
this allows for signalling cascades to proceed and induce activation
5
Q
A