c39 Flashcards

1
Q

what is immunology

A

the study of the immune system, the ways in which our bodies fight off invading organisms and infection

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2
Q

minor infections can be fatal if we don’t have a proper working what

A

immune system

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3
Q

cells, tissues and molecules involved in defending us

A

immune system

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3
Q

resistant to infection

A

immune (having immunity)

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3
Q

disease causing agents

A

pathogens

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3
Q

variolation

A

deliberate infection of small pox

prevention of disease by inhalation or insertion of pustules into cuts from smallpox infected individuals into those not infected

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3
Q

who invented vaccination

A

Jenner

Jenner observed milkmaids that had been infected with cowpox, didn’t catch small pox

Jenner inoculated a child with cowpox before infecting them purposely with small pox
RESULT: child did not catch smallpox

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3
Q

Who provided the first human vaccine

A

Louis Pasteur

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4
Q

how did Louis Pasteur create the rabies vaccine

A
  • used an old bacterial culture of Cholera to infect chickens
  • chickens did not die
  • exposed these chickens to fresh Cholera, they DID NOT die

conclusion: aging bacterial cultures = weakened or attenuated (reduced) strains…. can be used to immunize or vaccinate

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5
Q

fragment of pathogen

A

antigen

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6
Q

vaccines expose us to what in order to induce an immune response

A

vaccines expose us to non-lethal doses of pathogen or antigen to induce an immune response

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7
Q

significant reduction of infection due to majority of population being immune

A

herd immunity

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8
Q

skepticism around vaccines grew after what

A

MMR vaccine “was linked” to autism WHICH IS FALSE

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9
Q

what general happens with transplantation and the immune system

A

typically, the immune system recognizes a transplanted organ as foreign (NOT THE SELF) and rejects it

so we use genetic matching and immunosuppressive drugs to help transplant success

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10
Q

good bacteria is also called

A

commensal bacteria

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11
Q

do we need vaccines for all diseases?

A

no

some pathogens (pathogens lead to disease) are easily controlled with hygiene, clean water

some pathogens are also non-lethal

12
Q

branch of the immune system that defends the body against pathogens by using immune cells rather than antibodies

  • involves T cells and is effective against intracellular pathogens
A

cellular immunity by Elie Metchnikoff

uses phagocytes etc

13
Q

cells that ingest foreign material/pathogens

A

phagocytes

14
Q

branch of the adaptive immune system that protects the body by producing antibodies to target and neutralize extracellular pathogens

primarily mediated by B cells and their secreted antibodies

A

humoral immunity discovered by Von Behring and Kitasato

15
Q

something in serum collected from blood transferred immunity to animals that were never infected

  • contains antibodies specific to one or more antigens
A

antiserum

16
Q

antiserum contains something that could clump bacteria and neutralize toxins, what is this something

A

antibodies = gamma globulins = immunoglobulins

17
Q

immunity that develops when the body produces its own antibodies and immune cells in response to a pathogen or a vaccine

A

active immunity

18
Q

immunity that is acquired when antibodies are transferred to a person from another source

A

passive immunity

19
Q

occurs after exposure to a pathogen (ex. recovering from chickenpox)

A

natural active immunity

20
Q

occurs after receiving a vaccine that stimulates the immune system to produce a response without causing disease

A

artificial active immunity

21
Q

occurs naturally, such as the transfer of antibodies from a mother to her baby through the placenta or breast milk

A

natural passive immunity

22
Q

occurs when a person receives antibodies through an injection

A

artificial passive immunity

23
Q

what type of immunity is short-lived lasting weeks to months because the body does not produce memory cells

also develops immediately because the antibodies are provided directly

A

passive immunity

24
Q

what type of immunity is long-lasting, often lifelong, because it leads to the formation of memory cells that “remember” the pathogen

also takes days to weeks to develop because the immune system needs time to recognize the antigen and respond

A

active immunity