c39 Flashcards
what is immunology
the study of the immune system, the ways in which our bodies fight off invading organisms and infection
minor infections can be fatal if we don’t have a proper working what
immune system
cells, tissues and molecules involved in defending us
immune system
resistant to infection
immune (having immunity)
disease causing agents
pathogens
variolation
deliberate infection of small pox
prevention of disease by inhalation or insertion of pustules into cuts from smallpox infected individuals into those not infected
who invented vaccination
Jenner
Jenner observed milkmaids that had been infected with cowpox, didn’t catch small pox
Jenner inoculated a child with cowpox before infecting them purposely with small pox
RESULT: child did not catch smallpox
Who provided the first human vaccine
Louis Pasteur
how did Louis Pasteur create the rabies vaccine
- used an old bacterial culture of Cholera to infect chickens
- chickens did not die
- exposed these chickens to fresh Cholera, they DID NOT die
conclusion: aging bacterial cultures = weakened or attenuated (reduced) strains…. can be used to immunize or vaccinate
fragment of pathogen
antigen
vaccines expose us to what in order to induce an immune response
vaccines expose us to non-lethal doses of pathogen or antigen to induce an immune response
significant reduction of infection due to majority of population being immune
herd immunity
skepticism around vaccines grew after what
MMR vaccine “was linked” to autism WHICH IS FALSE
what general happens with transplantation and the immune system
typically, the immune system recognizes a transplanted organ as foreign (NOT THE SELF) and rejects it
so we use genetic matching and immunosuppressive drugs to help transplant success
good bacteria is also called
commensal bacteria