BIOCHEM Chp.5 Lipids Flashcards

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1
Q

What are the diff b/w saturated and unsaturated FA?

A

Saturated - only have single bonds, have greater van der Waals forces, and therefore more structural and stable, solid at room temp
unsaturated - 1 or more double bonds which introduce kinks in the chain, and make it difficult to solidify, liquid at room temp

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2
Q

What are steroids?

A

metabolic derivatives of terpenes made up of 4 cycloalkane rings (3 cyclohexane and 1 cyclopentane)

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3
Q

What is the role of steroids?

A

they regulate gene expression and metabolism

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4
Q

What are some important steroid hormones?

A

testosterone, estrogen, cortisol, aldosterone

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5
Q

What is the role of cholesterol in the cell membrane?

A

it regulates membrane fluidity - at low temps, it keeps the membrane from solidifying, and at high temps, it hold the membrane intact and prevents it from becoming too permeable

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6
Q

What are the fat-soluble vitamins?

A

Vit. A, D, E, and K

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7
Q

What attached the hydrophilic head group of the phospholipid membrane?

A

phosphodiester linkages which determines the function of the phospholipid

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8
Q

What is the backbone of glycerophospholipids?

A

glycerols

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9
Q

What lipid is the major component of the myelin sheath?

A

sphingomyelins - made up of phosphatidylcholine and phosphatidylethanolamine head groups

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10
Q

What are waxes?

A

long-chain FA esterified to long-chain alcohols

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11
Q

What is isoprene?

A

a 5-carbon molecule

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12
Q

What are the roles of prostaglandins?

A

smooth muscle contractions, regulation of body temp, sleep and wake cycle, fever, and pain

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12
Q

How many units make up a monoterpene?

A

2 isoprenes

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13
Q

What are prostaglandins?

A

autocrine and paracrine signaling molecules that regulate cAMP levels

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14
Q

What is the role of Vit. A/carotene?

A

metabolized to retinal for vision and retinoid acid for gene expression in epithelial development

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15
Q

What is the role of Vit. D/cholecalciferol?

A

metabolized to calcitriol in the kidneys and regulates calcium and phosphorus homeostasis in the intestines to increase their absorption, promoting bone formation

16
Q

What is the role of Vit. E/tocopherols?

A

acts as a biological antioxidant - their aromatic rings destroy free radicals, preventing oxidative damage

17
Q

What is the role of Vit. K/Phylloquinone and menaquiones?

A

important for the formation of prothrombin, a clotting factor. it also performs posttranslational modifications on several proteins, creating calcium-binding sites

18
Q

What are adipocytes?

A

large triacylglycerols deposits

19
Q

What is saponificationn?

A

the ester hydrolysis of triacylglycerols using a strong base like sodium or potassium hydroxide

20
Q

What is the role of soaps?

A

they act as surfactants, forming micelles that can dissolve liquid soluble molecules in their FA core, and wash away water because of their shell of carboxylate head groups

21
Q

What are triglycerols composed of?

A

a glycerol backbone esterified to 3 FA. used as energy storage