8.2.3 Diagnostic Medicine

Question 1

Describe the spectrum that is used to determine whether a test is necessary. What are the two thresholds and three areas on this spectrum?

Answer 1

Question 2

How is sensitivity calculated?

Answer 2

TP / (TP+FN)

Question 3

Describe the graph that compares sensitivity and specificity. Where are useless tests located? Where are useful tests located?

Answer 3

Question 4

What are the two factors that impact the clinical implication of a test result?

Answer 4

Pretest probability of the disease

Test accuracy

Question 6

What is used to measure diagnostic test accuracy?

Answer 6

Sensitivity AND Specificity

Question 7

What is sensitivity?

Answer 7

Ability of a test to correctly identify those with disease (true positives)

Question 8

What is specificity?

Answer 8

The proportion of negatives that are correctly identified as such (healthy people who are correctly identified as not having the conditon - True Negative)

Question 9

What process is used clinically to achieve a diagnosis?

Answer 9

Hypothetical-deductive method

Question 10

Calculate a post-test probability from a pre-test probability, sensitivity, and specificity and test result

Answer 10

Question 11

How is specificity calculated?

Answer 11

TN / (TN+FP)

Question 12

What information is required to determine the diagnostic accuracy of a test?

Answer 12

Sensitivity and Specificity

CANNOT DETERMINE WITHOUT BOTH!!!