2.3.3 Peripheral Neuropathy Flashcards
What is axonotmesis? What is the recovery period dependent upon?
What is the treatment for the different types of distal symmetric peripheral neuropathy?
Diabetic: Blood sugar control and pain management
Cryptogenic: symptom control
What are the three fundamental concepts used in clinical diagnosis of peripheral nerve lesions?
Where is the lesion (focal, diffuse, midline, multifocal)
Pattern of involvment (length dependent-axonopathy, proximal weakness present-myelinopathy)
Time Course
What are some potential causes of mononeuropathy multiplex?
Vasculitis, Lyme dz, Leprosy, Hereditary
What clinical workup can be done to distinguish b/t the two types of distal symmetric peripheral neuropathies– diabetes and cryptogenic?
Fasting blood glucose
What is neurotmesis? What is the recovery?
What are the most common causes of distal symmetric peripheral neuropathy?
Dibetic Peripheral Neuropathy and Cryptogenic Sensory Polyneuropathy (CSPN)
What is neuropraxia? What is the typical recovery period?
What are the two main symptoms of inflammatory demyelinating polyneuropathies?
Diffuse weakness including proximal muscles
Generalized Areflexia
What condition follows a cool dependent pattern of peripheral nervous system involvement?
Why are the longest neurons selectively vulnerable?
Since they’re so long, they require the most energy and cellular products to sustain their axonal transport. Thus, they are most vulnerable to insult
