Yersinia Flashcards

1
Q

Gram stain

A

Gram negative

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2
Q

Morphology

A

Rod shaped, bipolar stain look like safety pin

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3
Q

Oxygen requirements

A

Facultatively anaerobic

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4
Q

Do the ferment lactos

A

no

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5
Q

Y. pestis disease

A

Plague

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6
Q

Y. Pseudotuberculosis

A

Enterocolitis and mesenteric lymphadenitis in birds, rodents, and sometimes domestic animals. Generalized nodular abscesses

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7
Q

Y. enterocolitica disease

A

Enterocolitis and mesenteric lymphadenitis in humans and domestic animals. Foodbourne pathogen

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8
Q

Habitat of enterocolitica and pseudotuberculosis

A

GI tract and lymph nodes especially pigs (enterocolitica)

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9
Q

Lymph nodes and lymphoid tissue trophism

A

-Y. pestis: site of entry
-Y. pseudotuberculosis and entercolitica: Peyers patches and mesenteric lymph nodes

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10
Q

Habitat of pestis

A

Rodents, rabbits, squirrels, prairie dogs and others in sporadic pockets in US and europe and asia

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11
Q

Modes of infection of plague

A

-Flea bites
-Inhale aerosols
-Contact with infected person or dead animals
-Cat bites
-Ingestion (in cats)

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12
Q

Sylvatic plague

A

Plague in rodents where they serve as maintenance hosts and transmitted by fleas. Source of infection to animals and humans

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13
Q

Virulence factors of pestis

A

-Fraction 1 protein capsular
-Capsule
-LPS
-Yersiniobactin: siderophore
-Toxins

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14
Q

Toxins in pestis

A

-Yops
-LerV
-Murine toxin
-Pesticin
-Coagulase

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15
Q

Plague in domestic animals

A

Cats highly susceptible. Other animals may get infected by flea bites or eating forages by contaminated rodents
-Dogs get infected but no clinical signs

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16
Q

Forms of feline plague

A

-Bubonic
-Speticemic
-Pneumonic

17
Q

Clinical signs of feline plague

A

-Fever, depression, and anorexia
-Swollen lymph nodes (submandibular)

18
Q

Treatment of feline plague

A

Bubonic may respond
-Aminoglycosides
-Tetracyclines
-Chloramphenicol

19
Q

Enteric yersiniosis

A

More common in sheep, goats, and cattle
-Frequently isolate from feces of normal animals

20
Q

Clinical signs of enteric yersiniosis

A

-Diarrhea
-Jejunum and ileum most frequently affected
-May become systemic

21
Q

Incubation of Y. enterocolitica

A

24-36 hrs

22
Q

Signs of Y. enterocolitica

A

-Abdominal pain
-Fever
-Headache
-Vomiting
-Diarrhea
-Severe in younger people

23
Q

Food bourne pathogens

A
  1. Staphylococcus aeurus
  2. STEC O157:H7
  3. Salmonella enterica
  4. Yersinia enterocolitica
24
Q

Y. ruckeri

A

Fish pathogen causing red mouth disease.
-Subcutaneous hemorrhage around the mouth

25
Q

Enterobactericea resistent

A

Resistant to carbpenems and other antimicrobials

26
Q

Mechanisms of enterobactiericea

A
  1. Carbapenemase
    -Beta lactamase enzymes
27
Q

Y. enterocolitica special characteristic

A

Psychrotroph grow well in cold