Pseudomonas Flashcards
Gram stain
Gram negative rods
Oxygen requirements
Facultatively anaerobic
Special characteristics of pseudmonas, aeromonas, burkholderia
Oxidative metabolism (oxidase positive)
and nonfermentative
Is pseudomonas motile
Yes
Pseudomonas pigment
Pyocyanin ( green blue) and fluoroscien (yellow/green)
Special characteristics of P. aeruginosa
-Smells like grape
-Aminoacetophenone
-Hemolytic
Habitat
-Skin
-Mucous membrane
-Intestinal tract
-Feces
-Water
-Soil
-These have lower virulence and are opportunistic
Modes of infection
-Wound infections
-Oral
-Inhalation
-Injections and catheterizations
-Into teat
Predisposing factors
-Defect in defense mechanisms
-Major nosocomial
-Immunocompromised
Virulence factors
-Exotoxins: A,S,T, U, and V
-Protease
-Hemolysin (phospholipase)
-Pyocins
-Endotoxins
-Pili
-Flagella
-Clinical isolates produce more toxins
Pathogenicity
Either cause tissue damage due to toxins in acute disease or tissue damage due to immune response in chronic disease. Leads to suppurative and necrotizing
Swine disease
-Necrotic pneumonia, rhinitis, enteritis
-Abscesses
-UTI and GTI
Cattle diseases
-Abscesses at infection sites
-Enteritis
-Mastitis
-Pneumonia (foreign body)
-UTI and GTI
Horse disease
-Genital tract infections
-Corneal ulcerations (sand from racing)
-Guttural pouch infection
-Pneumonia
Dog and cat disease
-Otitis externa
-Prostatitis
-Cystitis
-Dermatitis
-Opthalmitis
-Post op infections
Poultry diseases
-Septicemia
-Respiratory infections
Sheep diseases
-Green wool dermatitis
Minks and chinchillas diseases
Hemorrhagic pneumonia due to inhalation and is very fata
Human infections
-Skin infections, especially burn patients
-Catheter site infections
-Lung infections in CF patients
Control measures
-No commercial vaccines
-Bacterins may help
Treatment
-Need to do antibiotic susceptibility
-Gentamicin
-Fluoroquinolone
-B lactam (imipenam)
