Burkholderia

Question 1

Gram stain

Answer 1

Gram negative rods

Question 2

Motility

Answer 2

Not flagellated and non-motile

Question 3

B. mallei diseases

Answer 3

Glanders

Question 4

B. mallei Mode of infection

Answer 4

-Ingestion
-Directed contact with infected animal
-Inhalation of infectious droplets
-Occupation disease of veterinarians

Question 5

Species affected by B. mallei

Answer 5

-equines
-Dogs
-Cats
-Goats
-humans

Question 6

Pathogenesis of B. mallei

Answer 6

Enter through mucosa and then to regional lymphatics then into the blood-> lungs and other organs

Question 7

Glanders types

Answer 7

-Cutaneous (Farcy)
-Lung lesions
-Nodules in nasal pathogens (purulent discharge)

Question 8

Diagnosis of B. mallei

Answer 8

Bacterial isolation
Mallein skin test

Question 9

Virulence factors of B. mallei

Answer 9

-Not sure really

Question 10

B. pseudomollei diseases

Answer 10

Meliodosis in tropical areas

Question 11

Animals affected by B. pseudomallei

Answer 11

-Cats
-Dogs
-Pigs
-Goats
-Sheep
-Horses
-Cattle

Question 12

Control measures of B. mallei

Answer 12

-No vaccine
-Early detection and quarantine
-Slaughter animals infected

Question 13

Treatment of B. mallei

Answer 13

-Tetracyclines
-streptomycin
-Sulfonamides

Question 14

Mode of infections of B. pseudomallei

Answer 14

-Rodents to man by insects
-Trauma (wounds)
-Ingestion
-Inhalation

Question 15

Virulence factors of B> pseudomallei

Answer 15

-Endotoxin
-Exotoxins
-Protease
-Lipase
-Lecithinase

Question 16

Types of toxins in B. pseudomallei

Answer 16

-Lethal and necrotizing
-Lethal only

Question 17

Meliodosis

Answer 17

-Endemic in tropical regions
-Infection gets disseminated and abscess may develop in organs
-looks like glanders in horses