Histotoxic clostridium Flashcards
Bacillary hemoglobinuria (Red water disease)
C. haemolyticum in pasture cattle
-Endemic to liver fluke areass
Virulence factor of C. haemolyticum
Beta toxin
Pathogenesis of C. haemolyticum
Ingest spores-> blood-> liver-> germination of spores-> produce Beta toxin-> blood hemolysis
Clinical signs of Bacillary hemoglobinuria
-Fever
-Depression
-Arched back
-Hemoglobinuria
-High mortality
-Hemorrhage through
-Hepatic infarcts
Diagnosis of bacillary hemoglobinuria
Phospholipase C in liver
Treatment of bacillary hemoglobinuria
Antiserum and penicillin or tetracycline
-BLood transfusion and fluids
Prevention of bacillary hemoglobinuria
Eliminate liver flukes
-Bacterins
Gas gangrene
Clostridium noyvi A
Infectious necrotic hepatitis (Black disease)
C. noyvi type B
Clinical signs of Infection necrotic hepatitis
-Sudden death
-Nonspecific
Lesions of infecitous necrotic hepatitis
-Necrotic areas in the liver
-Hemorrhagic subQ
-Edema and congestion
-Blackening of the carcass surface
Prevention of infectious necrotic hepatitis
Control flukes Bacterin
Black leg
Clostridium chauvoei
-Effects cattle from 6mo to 2 years
Virulence factors of Black leg
-Ccta
-Cytolysins
-Hyaluronidase
-DNAse
-Neuramindase
Clinical signs of black leg
Swellin in moscues of one or more leg
-Emphysema (gas) in musculature (crepitation
-Fever
-Rumen stasis
-Depression
-ANorexia
-Lamenss
-Muscle swelling
-Muscle is black or brown
-Muscle may slough off
