Histotoxic clostridium Flashcards
Bacillary hemoglobinuria (Red water disease)
C. haemolyticum in pasture cattle
-Endemic to liver fluke areass
Virulence factor of C. haemolyticum
Beta toxin
Pathogenesis of C. haemolyticum
Ingest spores-> blood-> liver-> germination of spores-> produce Beta toxin-> blood hemolysis
Clinical signs of Bacillary hemoglobinuria
-Fever
-Depression
-Arched back
-Hemoglobinuria
-High mortality
-Hemorrhage through
-Hepatic infarcts
Diagnosis of bacillary hemoglobinuria
Phospholipase C in liver
Treatment of bacillary hemoglobinuria
Antiserum and penicillin or tetracycline
-BLood transfusion and fluids
Prevention of bacillary hemoglobinuria
Eliminate liver flukes
-Bacterins
Gas gangrene
Clostridium noyvi A
Infectious necrotic hepatitis (Black disease)
C. noyvi type B
Clinical signs of Infection necrotic hepatitis
-Sudden death
-Nonspecific
Lesions of infecitous necrotic hepatitis
-Necrotic areas in the liver
-Hemorrhagic subQ
-Edema and congestion
-Blackening of the carcass surface
Prevention of infectious necrotic hepatitis
Control flukes Bacterin
Black leg
Clostridium chauvoei
-Effects cattle from 6mo to 2 years
Virulence factors of Black leg
-Ccta
-Cytolysins
-Hyaluronidase
-DNAse
-Neuramindase
Clinical signs of black leg
Swellin in moscues of one or more leg
-Emphysema (gas) in musculature (crepitation
-Fever
-Rumen stasis
-Depression
-ANorexia
-Lamenss
-Muscle swelling
-Muscle is black or brown
-Muscle may slough off
Treatment of black leg
Penicillin or antitoxin
Burn or bury carcass to limit soil contamination
Vaccine for black leg
Bacterin
Hemorrhagic abomastitis
Associated with frozen succulent feed
Clostridium septicum
-No clinical signs, sudden death
-Edema, hemorrhage, necrosis of mucosa and submucosa
Polioencephalomalacia
Clostridium sporogenes
