Kleibsella

Question 1

Two important species

Answer 1

pneumoniae and aerogenes

Question 2

K. pneumoniae colonies

Answer 2

Thick capsule, mucoid colony

Question 3

K. pneumoniae infections

Answer 3

Humans: nosocomial pathogen
Animals: opportunistic pathogen
-Pneumonia
-UTI
-Meningitis
-Mastitis
-Metritis and vaginitis

Question 4

Mode of infection

Answer 4

-Direct contact with contaminated materials
-Breeding stallions may be carriers
-Milking machines, bedding etc

Question 5

Virulence factors

Answer 5

-Endotoxin
-Capsule
-Urease

Question 6

Control measures

Answer 6

1. Sanitation and management
2. Antibiotic tx
3. No vaccine

Question 7

Diseases of aerogenes

Answer 7

-Mastitis in cows
-UTIs in dogs

Question 8

Klebsiella resistance

Answer 8

Carbapenemase is a type to beta lactamase
-Leads to high mortality
-Limited options for tx

Question 9

Cronobacter sakazaki

Answer 9

Opportunistic and emerging food borne pathogen
-Affects infants with meningitis and necrotizing enterocolitis

Question 10

Serratia marcesens

Answer 10

Gram negative, facultatively anaerobic, rod shaped, non lactose fermenter

Question 11

S. marcescens disease

Answer 11

-Mastitis in cows
-UTIs
-Septicemia in chickens
-Used as indicator organisms to study spread
-Zoonotic

Question 12

Most common causes of bovine mastitis

Answer 12

-S. aureus
-S. agalactiae
-S. dysgalactiae
-S. uberis
-E. coli/K. pneumoniae/K. aerogenes

Question 13

What organisms can cause mastitis through the blood stream

Answer 13

-Mycoplasma and brucella