Week 6 - IBD Medications Flashcards
what is a 5-aminosalicyclate
- group of meds used to treat inflammation in the gut
- anti-inflammatory agents for IBD
what is an example of 5-aminosalicyclate
sulfasalazine
what is the indication of sulfasalazine
- mild to moderate IBD
what is the anticipated effcet of sulfasalazine
- reduce inflammation in the GI tract
list possible side effects of sulfasalazine (5)
- nausea
- fever
- rash
- arthralgia
- hematologic disorders
what is arthralgia
- discomfort, pain, or inflammation arising from any part of a joint
describe nursing assessment for sulfasalazine
- improvement of GI symptoms
- periodic CBC
what is the MOA of sulfasalazine (2)
- suppresses prostaglandin synthesis
- suppresses the migration of inflammatory cells
what are corticosteroids
- steroid hormones
- includes mineralocorticoids and glucocorticoids
what are glucocorticoids
- drugs that produce physiologic effects at low doses
- and pharmacologic effects at high doses which can be used to treat inflammatory disorders
what are 2 types of glucocorticoids that can be used for IBD
- cortisone
- dexamethasone
describe the indication for glucocorticoids r/t IBD
- moderate to severe IBD
what is the anticipated effects of glucocorticoids r/t IBD
- reduce inflammation in the GI tract
list side effects of dexamethasone (5)
- adrenal suppression
- increased risk of infection (immunosuppresion)
- osteoporosis
- sodium & water retention
- potassium loss
describe nursing assessment for dexamethasone
- improve of GI symptoms
- signs of infection