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NURS 2514 > Week 6 - IBD Medications > Flashcards

Week 6 - IBD Medications Flashcards

1
Q

what is a 5-aminosalicyclate

A
  • group of meds used to treat inflammation in the gut

- anti-inflammatory agents for IBD

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2
Q

what is an example of 5-aminosalicyclate

A

sulfasalazine

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3
Q

what is the indication of sulfasalazine

A
  • mild to moderate IBD
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4
Q

what is the anticipated effcet of sulfasalazine

A
  • reduce inflammation in the GI tract
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5
Q

list possible side effects of sulfasalazine (5)

A
  • nausea
  • fever
  • rash
  • arthralgia
  • hematologic disorders
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6
Q

what is arthralgia

A
  • discomfort, pain, or inflammation arising from any part of a joint
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7
Q

describe nursing assessment for sulfasalazine

A
  • improvement of GI symptoms

- periodic CBC

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8
Q

what is the MOA of sulfasalazine (2)

A
  • suppresses prostaglandin synthesis

- suppresses the migration of inflammatory cells

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9
Q

what are corticosteroids

A
  • steroid hormones

- includes mineralocorticoids and glucocorticoids

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10
Q

what are glucocorticoids

A
  • drugs that produce physiologic effects at low doses

- and pharmacologic effects at high doses which can be used to treat inflammatory disorders

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11
Q

what are 2 types of glucocorticoids that can be used for IBD

A
  • cortisone

- dexamethasone

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12
Q

describe the indication for glucocorticoids r/t IBD

A
  • moderate to severe IBD
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13
Q

what is the anticipated effects of glucocorticoids r/t IBD

A
  • reduce inflammation in the GI tract
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14
Q

list side effects of dexamethasone (5)

A
  • adrenal suppression
  • increased risk of infection (immunosuppresion)
  • osteoporosis
  • sodium & water retention
  • potassium loss
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15
Q

describe nursing assessment for dexamethasone

A
  • improve of GI symptoms

- signs of infection

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16
Q

what type of med is used after glucocorticoids for moderate to severe IBD

A
  • infliximab
17
Q

what type of med is infliximab

A
  • immuno-modulator (monoclonal antibody)
18
Q

what is the MOA of infliximab

A
  • TNF antibody against TNF
19
Q

what is TNF

A
  • tumour necrosis factor
  • a key immunoinflammatory modulator
  • plays a role in IBD
20
Q

list 2 side effects of infliximab

A
  • increased risk of infection

- infusion rxn

21
Q

what is an infusion rxn (5)

A
  • fever
  • chills
  • pruritis
  • urticaria
  • cardiopulmonary rxn (chest pain, hypotension, HTN, dyspnea)
22
Q

what med is used for severe IBD

A
  • cyclosporine
23
Q

what type of med is cyclosporine

A
  • immunosuppressants
24
Q

describe assessment for infliximab

A
  • improvement of GI symptoms

- monitor for infection

25
Q

what is the anticipated effect of cyclosporine

A
  • reduce inflammation of the GI tract
26
Q

what are side effects associated with cyclosporine (3)

A
  • renal impairment
  • neurotoxicity
  • generalized suppresion of the immune system
27
Q

what is the MOA of cyclosporin

A
  • acts on helper T cells to suppress immune system
28
Q

describe nursing assessment of cyclosporin

A
  • improvement of GI symptoms

- monitor for infection

29
Q

what antidiarrheal drug can be used for IBD

A
  • loperamide
30
Q

what is the indication for loperamide (2)

A
  • pain related to rectal spasm

- diarrhea

31
Q

what is a side effect associated with loperamide

A
  • constipation
32
Q

what is the anticipated effects of loperamide

A
  • decrease GI motility

- relive rectal spams

33
Q

describe nursing assessment of loperamide

A
  • symptoms relief: less BMs and rectal spasm
34
Q

what antimicrobial drug can be used for IBD

A
  • metronidiazole (flagyl)
35
Q

what is the anticipated effect of metronidiazole

A
  • eradication of H pylori for pts with peptic ulcer disease
36
Q

what type of vitamin can be used in IBD

A
  • ferrous sulfate
37
Q

what is the indication for ferrous sulfate

A
  • iron deficiency anemia
38
Q

list adverse effects of ferrous sulfate (2)

A
  • GI disturbances (N, CD, pyrosis, bloating)

- staining of teeth

NURS 2514 (75 decks)

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