Week 3 - Seminar Flashcards
what are the 3 primary functions of the urinary system
- filter waste from blood
- balance electrolytes & acid/base
- excrete metabolic wastes
what are 3 secondary functions of the urinary system
- regulate BP
- regulate bone density
- regulate erythropoiesis
define chronic kidney disease
- a state in which the kidneys no longer function adequately to rid the body of wastes
- unable to maintain homeostasis
CKD is an example of_____
- altered elimination
list 7 risk factors of CKD
- diabetes
- HTN
- smoking
- heart disease
- over 65
- meds
- ethnicity
which ethnicities are risk factors for CKD (7)
- indigenous
- asian
- south asian
- pacific island
- african
- caribbean
- latin canadian
what 2 things are monitored for those at risk of CKD
- blood work
- urine
diagnosis of CKD is made when…
GFR < 60 ml/min/1.73 m2 for 3 months or longer
what is the most common renal disease that leads to dialysis & transplantation
- diabetic nephropathy
how long after the onset of diabetes does proteinuria appear?
- 10 years
what is an important way to prevent renal disease in pts w diabetes
- blood glucose control
how many clinical stages of CKD are there?
- 5
describe symptoms & GFR in stage 1
- GFR = >90
- likely asymptomatic bc kidneys can compensare well
descibre symptoms & GFR in stage 2 (2)
- GFR = 60-89
- may have decreased ability to conc urine
- develop symptoms of anemia
describe symptoms in stage 3-4 of CKD (5)
- electrolyte & fluid imbalances
- oliguria
- more severe anemia
- metabolic acidosis
- azotemia
what is stage 5 of CKD? describe symptoms instage 5 of CKD (3)
- end stage renal disease needing dialysis/transplant
- anuria
- severe electrolyte & fluid imbalance
- uremia
is CKD progressive or sudden?
- progressive deterioration
what 3 functions of the kidenys are lost during CKD
- excretory
- regulatory
- endocrine
list 6 substances the kidneys retain during CKD
- urea
- creatinine
- phenols
- hormones
- electrolytes
- water
what is uremia
- constellation of symptoms r/t to buildup of waste products & excess fluid
at what stage(s) do we see uremia in CKD
- 4/5
what should we consider during health history for CKD (8)
- current health (OPQRSTU)
- PMHx (diseases that are risk factors)
- PSHx
- famHx
- meds
- allergies
- social
- occupation/enviro
why is it important to ask about meds for health history of CKD
- some meds are nephrotoxic
- consider compliance for drugs that help reduce risk factors ex. diabetes meds –> glucose regulaion is important for preventing kidney disease
list 5 electrolyte that will be effected by CKD
- potassium –> hyperkalemia
- sodium –> normal or low –> dilutional (from retaining so much water)
- calcium
- phosphate
- magnesia –> hypermagnesia
what causes hypermagnesia in CKD
- will only occur if ingesting Mg
what are 2 examples of sources of magnesium
- supplements
- milk of Mg
list 2 symptoms r/t to hypermagnesia
- decrease in mental status
- dysarrthymia
what acid-base imbalance may occur due to CKD
- metabolic acidosis
what are symptoms of hyperkalemia
Muscle weakness
Urine output little or none
Resp failure (due to muscle weakness)
Decreased cardiac contractility (weak pulse, low HR again due to muscle weakness)
Early: muscle cramps/twitches
Rhythm changes (tall T waves, prolonged PR interval)
what are symptoms of hyponatremia
Stupor/coma
Abdominal cramping, NV
Lethargy
Trouble concentrating
Loss of urine & appetite, overactive bowel sounds
Orthostatic hypotension
Seizures, spasms of muscles
Shallow resp
what are 2 possible diagnostic test for electrolyte/acid-base imbalances r/t CKD
- electrolytes (for imbalances)
- ABGs (for metabolic acidosis)
list 3 hematological symptoms r/t to CKD
- anemia
- bleeding tendencies
- infection
list 3 causes of anemia r/t to CKD
- decreased erythropoitin
- dialysis –> causes damaged RBC
- frequent blood draws
what kind of anemia is seen in CKD
- normocytic (normal size)
- normochromic (conc of hgb is normal)
what causes bleeding tendencies r/t to CKD
- defect in platelet function r/t uremia
what causes infection r/t to CKD
- change in leukocyte function & altered immune response r/t aztoemia
describe physical assessment for hematological symptoms of CKD (4)
- observe for SOB, pale skin (for anemia)
- auscultate for tachy
- assess for unusual bleeding
- assess for infection
how can we assess for unusual bleeding
- easy bruising
- bleeding nose
- bleeding gums
- abdominal exam
- blood in stool
- signs of strok
how can we assess for infection (4)
- vital signs (temp)
- increased pain
- redness
- purulence
what are potential diagnostics for hematological signs of CKD (5)
CBC:
- low hgb
- increased WBC (infection)
- normal plt (defect, not thrombocytopenia**)
- normal pt/ptt
- ferritin/iron low
what are CNS symptoms of CKD (3)
- CNS depression
- seizures, coma (uncommon)
- peripheral neuropathy
what signs of CNS depression are seen in CKD (4)? what causes this?
due to uremia
- fatigue
- decreased loc
- irritability
- decreased conc
what are 4 signs of peripheral neuropathy
- restless legs
- paresthesia in feet/legs
- muscle weakness
- muscle twitch, asterixis
what is asterixis
- uncontrolled movement in hands = hand flapping
describe physical assessment of CNS symptoms of CKD (2)
- observe/ inspect thru change in conciousness, behavior, convo
- palpate extremities to assess for changes in sensation, unusual reflexes/tremors