Week 1 - Lymphoma Flashcards
1
Q
what are lymphocytes
A
- type of WBC
- specifically a type of agranular leukocyte
2
Q
what is the main function of lymphocytes
A
- their main function is related to the immune system
3
Q
what are the 2 subtypes of lymphocytes
A
- B cells
- T cells
4
Q
what are lymph nodes
A
- small clumps of lymphatic tissue found in groups along lymph vessels throughout the body
5
Q
what is the function of lymph nodes
A
- the filtration of pathogens & foreign particles that are carried by lymph fluid to the nodes
6
Q
what is the purpose of the lymphatic system?
A
- carries fluid from the interstitial spaces to the blood
- also returns excess interstitial fluid to the blood
- also plays a role in the immune system
7
Q
why is the function of returning excess interstitial fluid to the blood important?
A
- important in preventing the development of edema
8
Q
what is bone marrow
A
- soft material that fills the central core of bones
9
Q
what is the function of red bone marrow?
A
- produces blood cells thru differentiation of the hematopoietic stem cells
10
Q
what is lymphoma
A
- malignant neoplasms originating in the bone marrow and lymphatic structures resulting in proliferation of the lymphocytes
11
Q
what are the 2 major types of lymphoma
A
- Hodgkin’s disease
2. non-hodgkin’s lymphoma (NHL)
12
Q
what cells are effected in hodgkins vs non hodgkins?
A
- hodgkins = reed-sternburg cells
- non = B and T (mostly B)
13
Q
what are the clinical manifestations of lymphoma?
A
- enlarged lymph nodes
- B symptoms
- hepatomegaly & splenomegaly
- fatigue
- weakness
- tachycardia
- anemia
14
Q
what are B symptoms
A
- fever
- night sweats
- weight loss
15
Q
what are risk factors of lymphoma?
A
- infection w epstein barr virus
- genetic predisposition
- exposure to occupational toxins
- patients w HIV
- patients w immunosuppressive meds or have receieved chemo or radition
