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step 2 > uworld week of 7/27 > Flashcards

uworld week of 7/27 Flashcards

1
Q

Lynch syndrome cancers

A

colorectal
endometrial
ovarian

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2
Q

FAP cancers

A

colorectal
desmoids and osteomas
brain tumors

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3
Q

Von Hippel Lindau cancers

A

hemangioblatomas
clear rcc
pheo

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4
Q

MEN 1 cancers

A

Parathyroid
pituitary
pancreatic

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5
Q

when to start endometrial biopsy with Lynch?

when to hysterectomy?

A

30

40

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6
Q

RV failure signs

A 
elevated jvp
right ventricle 3rd heart sound
tricuspid regurgitate murmur
hepatomegaly with pulsatile liver
edema and acsities
pleural effusion
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7
Q

what dysfunction causes swelling in Cor pulmonate

A

pulmonary artery systolic pressure cause RV dysfunction

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8
Q

TX for asymptomatic PAC’s

A

nothing but stop drinking, smoking,and caffeine, give BB if symptomatic

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9
Q

Bacillary angiomatosis cause manifestation and tx

A

Bartonella henslae, cats or home less lice), vascular cutaneous lesions(papular, nodular, pedunculate)
organ involvement
fever, night sweats, fatigue
tx: doxy or erythromycin

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10
Q

Addisons labs

A

hyperK, hypoNa, eiosiophillia

high ACTH, low morning cortisol

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11
Q

patients with smoke inhalation injury imperically treated with_____ for ____

A

hydroxycoalbumin or sodiumthiosulfate to tx cyanide toxicity

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12
Q

why does cyanide cause met acidosis

A

reduces oxygen utilization by tissues by binding FE3+ stops ATP

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13
Q

why are multiple myeloma patients at increased risk for infection

A

impaired antibody production after bone marrow infiltrated

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14
Q

vitamin deficiency with long term metformin

A

B12

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15
Q

initial tx for hyperventilation syndrome

A

breathing retraining and reassurance

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16
Q

idiopathic transverse myelitis pathophys

A

immune destruction of spinal cord, often post infectious

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17
Q

idiopathic transverse myelitis clinical ft

A

bilat motor weakness, early flaccid (LMN), late spastic(UMN)
distinct sensory level
autonomic dysfunction

18
Q

idiopathic transverse myelitis dx

A

MRI T2 hyper intensity

LP: ⬆️ WBC⬆️ IgG index

19
Q

idiopathic transverse myelitis tx

A

high dose intravenous steroids

plasmapheresis

20
Q

RA patient with nephrotic syndrome

A

amyloidosis, multiple myeloma also increases risk of amyloidosis

21
Q

tx for sporotrichosis

A

3-6 months of itraconazole

22
Q

migrane prophylaxis meds

A

BB
TCA
Topiramate
divalproex sodium

23
Q

which thyroid cancer had increased calcitonin

A

medullary( the one in men 2 a and b

24
Q

meds for essential tremor

A

non selective BB like propranalol

anti seizure like primidone

25
Q

polyarthritis rheumatica tx

A

prednisone, watch for this in older people with elevated ESR and no other inflammatory markers

26
Q

what cancer do people with pernicious anemia get

A

gastric

27
Q

what are patients with nephrotic syndrome at an increased risk for

A

atherosclerosis due to hyperlipidemia and av thrombus due to loss of anti thrombin 3.

28
Q

older person holding things far away to read dx

A

presbyopia, caused by loss of lens elasticity

29
Q

what is telogen effluvium

A

acute diffuse nonimflamatory hair loss. triggered by illness of stress, treat by addressing underlying cause

30
Q

treatment escalation ankylosing spondylitis

A

NSAIDS/Cox-2
TNF alpha inhibitors like etanercept and infliximab
anti IL 17 like secukinbumab

31
Q

sacrocid electrolyte abnormality sometimes

A

hyper ca

32
Q

amioderone side effects

A 
Brady/❤️ block
QT prolongation --> torsades
chronic interstitial pneumonitis
hyper or hypothyroid
hepatitis
corneal micro deposits and optic neuropathy
bluegray skin
peripheral neuropathy
33
Q

tx for uric acid stone prevention

A

potassium citrate to alkalize urine

34
Q

how does sodium bicarb help TCA overdose

A

Sodium load will stop action on myocardial sodium channels.

35
Q

how does sodium bicarb help Aspirin overdose

A

urine alkalization increases excretion

36
Q

what test to do before methotrexate

A

liver function for sure

37
Q

long term cyclophosphamide is associated with

A

increased incidence of acute hemorrhagic cystitis and bladder carcinoma

38
Q

first tx for cocaine induced chest pain

A

Benzos, do normal heart attack things except BB if they are having a heart attack

39
Q

ATN casts

A

muddy brown

40
Q

most common med that causes angioedema

A

ACE-i

41
Q

what eye thing are storage weber kids at risk for

A

glaucoma

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