4/18 Flashcards
digoxin MOA
decrease extracellular Na
Fick’s principle
CO = rate of O2 used/(arterial o2-venous o2)
most common cause of secondary HTN
Renal DZ
what med is contraindicated in bilateral renal artery stenosis
ACEi-ischemia
what do alpha blockers end in
azosin
DM best HTN med
ACEi-delays kindness damage
DM contraindicated HTN meds
Thiazides, Beta blockers-impaired glucose tolerance
CHF best HTN meds
ACEi/ARB
Aldosterone agonist
B blocker
CHF contraindicated HTN meds
Ca2+ blockers-reduced rate and contractility
Post MI best HTN meds
ACEi/ARB
Aldosterone agonist
B blocker
BPH HTN med
alpha 1 blocker
migranes HTN med
verapamil, beta blocker
osteoporosis HTN med
thiazides-maintains Ca
pregnancy HTN meds allowed
Hydralazine
methyldop
LABATELOL
Nifedipine
who gets a statin
High ASCVD 40-75 7.5%
diabetes 40-75
ldl>190
MONABASH
Morphine O2 Nitro Aspirin BB ACEi Statin Heparin
V2-4 changes
Anterior LAD
V1-3 changes
septal (LAD)
2,3, avf
inferior (Posterior descending)
1, avl, V4-V6
Lateral (LAD or circumflex)
when do ventricular wall ruptures happen post MI
4-8 days
when are arrhythmia post MI
2-4 days
when is papillary necrosis post mi
5-10days
pericarditis post MI days
2-4
Dresslers post MI timeframe
2-8 weeks
Afib tx options
Anticoagulation BB Cardioversion Ca2+ blockers Digoxin
Class 1a MOA, Examples, Use
NA+ channel blocker prolonged action potential, Quinidine, Procanamide
PSVT, Afib, Aflutter, Vtach
Class 1B MOA, Examples, Use
NA+ channel blocker shortens action potential, Lidocaine, tocainide
Vtach
Class 1C MOA, Examples, Use
NA+ channel blocker no effect on action potential, flecainide propafenone
PSVT,Afib, Aflutter,
Class 2 MOA, Examples, Use
BB, -lol, PVC,PSVT,Afib, Aflutter,Vtach
Class 3 MOA, Examples, Use
K+ blockers, Amioderone, stall, bretylium,
Afib, Aflutter, Vtach (not bretylium)
Class 4 MOA, Examples, Use
Ca2+ blockers, verapamil, diltiazam,
PSVT, MAT,Afib, Aflutter
Adenosine MOA, Use
K+ activation ➡️ decreased cAMP
PSVT
COPD ❤️ thing
cor pulmonale
most common HF sign
S3
JONES criteria
Joints ❤️ Nodules Erythema Sydenham Chorea
besides st elevation what else is seen on pericarditis egg
PR depression
beck’s triad for for tamponade
hypotension, distended neck, distant heart sounds
Major Duke’s criteria
Serial blood cultures +
vegetation or access on echo
new onset regurg
blood cultures + coxiella burnetii
Acute endocarditis organism
staph aureus
step pneumonia
strep pyogenes
neisseria
Subacute endocarditis organisms
viridian’s strep
Enterococus
fungi
staph epididymus
endocarditis abs length
4-6 weeks
PVD only meds
pentoxyfylline and cilostazol
what dz associated with poly arthritis nodoasa
hep b and c
what system is spared in poly arthritis nodes
pulm
poly arthritis nodes marker
p-ANCA
Positive Sudan stain normal d xylose test
Assess for pancreatic insufficiency
Abnormal d xylose
Get small bowl biopsy
Sprue
Whipple
Bacterial overgrowth
Malabsorption low stool ph
Lactase deficiency
Malnutrition normal stool ph
Pernicious arena
Ileal dz
Bacterial overgrowth
Tropical sprue tx
Tetracyclines
Whipple sx
Arthralgia
Dementia
Other neuro
abdominal pain
Whipple tx
Bactrim or cefteiaxone for 1 year
What marker sometime + in UC
PANCA
Peutz jeghers syndrome
Polyps and hamaratoma. Mucocutaneous pigmentation of mouth hand and genitalia
Grey turner sign
Cullen sign in pancreatitis
Ecchymosis of flank
Periumbilical ecchymosis
Exocrine pancreases tumor markets
CEA CA19-9
Liver lab PBC
⬆️ Alk phos
⬆️ cholesterols
⬆️bili
Normal AST ALT
+ANA
PSC associated dz
UC
Hemochromatosis tx
Phlebotomy
Deferoxamine
Ceruloplasmin levels wilsons dz
⬇️
Wilson’s tx
Trientine penicillamine
Zinc
B6
Budd–Chiari syndrome
occlusion of the hepatic veins that drain the liver. It presents with the classical triad of abdominal pain, ascites, and liver enlargement.