uworld form 2 block 2 Flashcards

1
Q

Paget disease MOA

A

disorganized bone remodeling

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2
Q

Paget disease tx

A

bisphosphonates

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3
Q

Classic triad for hemochromatosis

A

cirrhosis, DM, skin pigmentation.

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4
Q

other sx of hemochromatosis besides classic triad

A
fatigue
arthopathy
hypogonadism
hypothyroid
cardiomyopathy 
increased infection from listeria, vibrio vulnerability. and yersinia enterocolitica
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5
Q

pre-e greater than or equal to 37 weeks tx

A

induce delivery

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6
Q

regular contractions no cervical change <34 weeks test

A

FFN, if + give bethamethasone

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7
Q

Dementia with Lewy bodies clinical picture

A

fluctuating cog/attention, well-formed visual hallucinations, and motor manifestations of Parkinson’s (rigidity, bradykinesia, postural instability) memory is usually affected later in disease course

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8
Q

delivery before 37 weeks unknown GBS status

A

Penicillin

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9
Q

EKG for Ventricular aneurysm

A

persistant ST elevation after recent MI with deep Q waves in same lead, look for limb ischemia

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10
Q

scurvy sx

A

petechial and perifolicular hemorrhages, mucosal bleeding, pridontal disease.

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11
Q

Thiamine B1 deficiency sx

A

beriberi, peripheral neuropathy, high output ❤️ failure, , confusion, ataxia, oculomotor abnormalities, memory impairment

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12
Q

B3 deficiency

A

pellagra:
dermatitis
dementia
Diarrhea

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13
Q

pyelonephritis in preg complication

A

ARDS
preterm labor
low birth weight

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14
Q

lab value abnormality antiphospholipid

A

prolonged ptt

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15
Q

mixing study for antiphospholipid

A

will NOT be corrected

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16
Q

mixing study for factor deficiency

A

Corrected

17
Q

good prognostic factors schizophrenia

A
later onset
female
acute onset 
\+sx
No family history
short duration of active sx
18
Q

Type 1 chemo

induced cardio toxicity ft

A

Anthracyclines(doxorubicin)-
myocyte necrosis causes fibrous replacement.
progression to overt ❤️ failure
less likely to be reversible

19
Q

Type 2 chemo

induced cardio toxicity ft

A

trastuzumab- myocardial stunning/hibernation without destruction
asymptomatic lv dysfunction
more likely reversible