tumor markers Flashcards
Calcitonin
medullary carcinoma of thyroid
Chromogranin A
neuroendocrine tumors- carcinoid/pheochromocytoma
CA 125
EPITHELIAL tumors of the OVARY
CA 19-9
Pancreatic adenocarcinoma
Prostate specific antigen (PSA)
prostate
CEA
carcinoma embryonicantigen (CEA): carcinomas of the lung, breast, pancreas, stomach, colon
beta-hCG
trophoblastic tumors: choriocarcinoma, hydatitidform mole, invasive mole
PLAP
placental alkaline phosphatase- seminomas
alpha fetal protein
non-seminomatous germ cell tumors: yolk sac, embryonal carcinoma.
if you see AP (alkaline phosphatase) what else should you look for? what others rise and when?
gamma-glutamyltransferase: AP and GGT rise in biliary tree diseases, AST/ALT usually rise before them.
angiosarcoma of the liver
vinyl chloride and arsenic
nitrosamines
gastric cancer
napthyline, cyclophosphamide
bladder cancer
aromatic carbons
bronchogenic carcinoma
asbestos
bronchogenic carcinoma
arsenic
angiosarcoma of the liver
alkylating agents
CHEMO: lymphomas, leukemias, many other cancers
azo dyes
aromatic amines
cervical cancer - MC
squamous cell carcinoma, HPV/Stds risk factors, tx is hysterectomy
Vagina: MC mass, MC tumor, MC cancer
MC mass: warts MC tumor: fibroma MC cancer: upper half - SCC of the cervix lower half: skeletal muscle...tumor: rhabdomyoma. cancer: rhabdomyosarcoma (sarcoma botyriodes)
Bartholin cyst
in vagina
congenital
fluctruan mass behind labia majora
complication: infections abscess formation
vaginal rhabdomyoma/rhabdomyosarcoma
rhabdomyosarcoma: 90% < 3 yrs of age
increased incidence in tuberous sclerosis
sarcoma botryoides: looks like a ball of grapes when removed
Prostate: MC tumor, MC cancer
MC tumor: BPH, MC cancer: adenocarcinoma
