transfusion reactions

Question 1

fine the first few hours of transfusion, but then develops fevers, chills, flank pain within 24 hours

Answer 1

acute hemolytic anemia

Question 2

urticaria, difficulty breathing within minutes of transfusion

Answer 2

allergic reaction

pre-formed antibodies

pt prob has IgA deficiency

Question 3

fevers and chills after blood transfusion but NO back pain

Answer 3

febrile nonhemolytic reactions

host antibodies against donor leukocytes

tx w/acetominophen and meperidine

Question 4

respiratory distress within hours of transfusion

Answer 4

transfusion related acute lung injury- white blood cells degranulate in pulmonary vasculature