Cardiopharm

Question 1

I’d Buy Liddy’s Mexican Tacos

Answer 1

Lidocaine, Mexiletine: class IB

Question 2

The Queen Proclaims Diso’s Pyramids

Answer 2

Quinidine, Procainamide, Disopyramide: Class IA anti-arrhythmics

Question 3

Can I have Fries Please

Answer 3

Flecainide, Propafenone: class IC

Question 4

1. IB is best in
2. IC is Contraindicated in

Answer 4

1. IB is Best in MI
2. IC is Contraindicated in structural and ischemic heart disease

Question 5

AIDS

Answer 5

Class III antiarrhythmics, potassium channel blockers

amiodarone, ibutlidie, dofetilide, sotalol

Question 6

Decreases slope of phase 0

Answer 6

Class IA, IB, IC

Class A > Class B < Class C

Question 7

increase in: AP duration, refractory period (ERP), QT interval. Has potassium channel blocking effect

Answer 7

Class IA- acts on IA

Question 8

preferentially effects ischemic tissues or depolarized purkinje/ventricular tissue.

Answer 8

IB: I’d Buy Liddy’s Mexican Tacos (lidocaine, MexileTINE)

decreases AP

phenytoin can act as a class IB

Question 9

1. especially re-entrant and ectopic SVT and VT
2. acute ventricular arrhythmias (especially post MI)
3. digitalis induced arryhthmias
4. SVTs, afib

Answer 9

1. Class IA
2. Class IB
3. Class IB
4. Class IC

Question 10

Decreases SA and AV action potentials by reducing cAMP mediated calcium influx during phase 4

what are the drugs in this category?

which drug has a similar suffix but not part of this class?

Answer 10

Class II beta blockers

1. metaprolol
2. atenolol
3. propanolol
4. carvedilol
5. esmolol
6. timolol

class III potassium channel blocker- sotalol

Question 11

decreases slope of phase

Question 12

1. headaches, tinnitus
2. reversible SLE like symptoms

Answer 12

1. cinchonism- quinidine
2. procainamide

Question 13

1. tosades de pointes
2. pulmonary fibrosis
3. hepatotoxicity
4. hypothyroidism
5. blue gray skin deposits
6. photodermatitis
7. bradycardia, heart block, HF

Answer 13

1. stotalol (excessive beta blockade) & ibutlide

2-7: amiodarone

Question 14

check PFTs, LFTs, and TFTs when using

Answer 14

amiodarone

Question 15

lipophilic and has class I, II, III, and IV effects

Answer 15

amiodarone

Question 16

used in afib, aflutter, Vtach

Answer 16

class III- potassium channel blockers

Vtach- amiodarone and sotalol

Question 17

effects are blunted by theophylline and caffeine

Answer 17

adenosine

Question 18

drug of choice in diagnosing/terminating forms of SVT

Answer 18

adenosine

Question 19

increases potassium efflux and hyperpolarizes cell, and decreases calcium influx

Answer 19

adenosine

Question 20

1. beta blockers A through M are
2. beta blockers N through Z
3. the only exceptison
4. appropriate beta blockers to manage HTN in asthmatics
5. appropriate beta blockers to manage HTN with mgiraines
6. appropriate beta blockers to manage HTN emergencies in the context of a pheochromocytoma

Answer 20

1. beta blockers A through M are: beta 1 selective
2. beta blockers N through Z: beta nonselective
3. carvedilol and labetolol: these block BOTH alpha 1 and beta receptors
4. beta-1 selective antagonists (beginning with A through M)
5. timolol
6. labetolol

Question 21

beta blockers with intrinsic sympathomimetic activity (ISA) and so contraindicated in stable angina

Answer 21

ISAs: pindolol and acebutolol

Question 22

1. causes orthrostatic hypotension with the initial dose
2. which class of drugs are these and what are they prescribed for?

Answer 22

1. alpha 1 antagonists- end with “sin”
2. hypertension and BPH