OMED Pulmonology Flashcards
Mild intermittent asthma
Intermittent asthma
Symptoms < 2 days a week
Symptoms do not interfere with normal activities.
Nighttime symptoms < 2 days a month.
Lung function tests (spirometry and peak expiratory flow[PEF]) = normal when the person is not having an asthma attack
Mild persistent
Symptoms > 2 days a week
Symptoms do not occur every day.
Attacks interfere with daily activities.
Nighttime symptoms - 3 to 4 times a month.
LFTs normal when the person is not having an asthma attack.
Moderate persistent asthma
Symptoms= daily.
Inhaled short-acting asthma medication is used every day.
Symptoms interfere with daily activities.
Nighttime symptoms occur more than 1 time a week, but do not happen every day.
LFTs abnormal (more than 60% to less than 80% of the expected value), and PEF varies more than 30% from morning to afternoon.
severe persistent asthma
Symptoms occur throughout each day.
Severely limit daily physical activities.
Nighttime symptoms occur often, sometimes every night.
Lung function tests are abnormal (60% or less of expected value), and PEF varies more than 30% from morning to afternoon.
Chronic Asthma Treatment
I - SABA II- SABA + ICS III - SABA + ICS + LABA IV - SABA + ↑ ICS + LABA Ref. oral prednisone
Asthma Drugs
SABA LABA ICS LTA Steroids Stabilizers
SABA- albuterol
LABAs- formoterol, salmeterol
ICS- beclomethasone, budesonide, fluticasone, mometasone
LTA- monetlukast, mometasone
steroids- predinsone (oral)
stabilizers - nedocromil, leukotriene antagonists
shortness of breath, wheezing, hyperresonant, prolonged expiration, exposure to trigger (cold air and allergens), CBC = eosinophilia
nasal polyps
Asthma
Path: reversible inflammation and bronchoconstriction
Dx:
pulmonary function tests (FEV1/FVC ↓, Reversible with bronchodilation, inducible with methacholine), skin tests = identify triggers
Tx - beta agonists, steroids, stabilizers
Wheezing, dyspnea, prolonged exhalation,
CBC showing eosinophilia, nasal polyps
asthma exacerbations
path- exposure to triggers Dx- clinical, but -xray to rule out worse causes -peak flow -NO PFTs
Tx
- IV methylprednisolone
- albuterol+ipratroprium
- steroid taper
f/u
- racemic epinephrine
- magnesium
- “stops wheezing” or CO2 rising –> intubate
wt loss, hemoptysis, dyspnea, pleural effusion in smoker or pt with exposure RFs
lung cancer
lung cancer
dx with biopsy choices and why
dx:
CXR –> CT scan –> biopsy (best)
biopsy:
- percutaneous if peripheral
- endoscopic US if proximal
- VATs if in the middle
- lobectomy ok too
lung cancer
tx
fu
tx
diagnose–> stage–> PFTs to discern if they can tolerate surgery or if they need chemo
f/u
annual low dose CT scan screen
- smoker within 15 yrs
- 55-80 yo
- > 30 pack year history
central mass in the lungs, hyponatremia or cushing’s like presentation
Small Cell Lung Cancer
path- smoking
dx- broncho/EUS
tx- chemo
central mass, hypercalcemia
Squamous Cell Lung Cancer
path: smoking
pt: central mass + paraneoplastic syndrome PTH-rp secreting tumor
Dx: broncho/EUS
tx: resection, chemo, rads
peripheral mass, pleural plaques
adenocarcinoma
path: peripheral mass, pleural plaques.
dx: percutaneous biopsy
tx: chemo/rads