OMED GI Flashcards
Colicky RUQ pain radiating to the shoulder, worse with fatty foods:
DX and TX
Cholelithiasis
Dx: RUQ US = gallstones in gallbladder
Tx: Ursodeoxycholic acid (non-surgical) or elective cholecystectomy
Constant RUQ pain
+Murphy’s sign
+ fever
+ ↑ WBC
Dx and tx
Cholecystitis
Dx: RUQ U/S then HIDA if scan is equivocal
Tx: NPO, IVF, cholecystectomy (urgent)
Constant RUQ pain painful jaundice murphy's sign (+) fever ↑ WBC
Dx and Tx
Choledocolithiasis plus/minus pancreatitis, hepatitis
Dx: RUQ US showing dilated CBD
MRCP if uncertain
Tx: NPO, IVF
ERCP urgently or cholecystectomy with intraoperative choleangiogram
RUQ pain Jaundice Fever Hypotension AMS
Dx and Tx
Cholangitis
Dx RUQ US dilated bilary duct
Tx: NPO, IVF + IV Abx (cipro or metronidazole), ERCP emergently
Biliary diseases and Locations
Cholelithiasis - gallstones in gallbladder
Cholecystitis - gallstone impaction in cystic duct
Choledocheolithiasis - gallstones in CBD
Cholangitis - gallstones in CBD with alarm symptoms (Charcot’s Triad or Reynold’s pentad)
Esophagitis diseases mnemonic
PIECE
Pill induced Infectious Eosinophilic Caustic Everything else (GERD, cancer)
Diagnosing esophagitis, generally
EGD with biopsy
Infectious esophagitis: pathogens and tx
Candida- oral thrush - fluconazole
HSV- oral lesions - val-acyclovir
CMV - linear lesions - val-agancyclovir
HIV- HAART therapy
Esophageal Disorders listed
Achalasia Scleroderma Esophageal spasm Schatzi Ring Esophageal webs Zenker's diverticulum Stricture - (GERD type IV) Cancer (GERD)
dysphagia with “knot” or ball of food stuck at GE junction
dx and tx
achalasia
1. barium swallow - bird's beak ↓ 2. Manometry - LES high tone ↓ EGD w/biopsy to rule out cancer (pseudoachalasia)
Tx: Myotomy - best but balloon dilation is the standard. botulinum if they’re a poor surgical candidate
Patient with relentless GERD, calcinosis, Raynaud’s phenomenon, dysphagia, sclerodactyly, and telangiectasia
Dx and tx
Scleroderma: CREST syndrome or systemic sclerosis
dx: barium swallow - normal ↓ Manometru - LOW tone LES ↓ EGD with bx - collagen deposition
Tx: PPI, FU with serology
“heart attack” symptoms exacerbated by cold liquids and improved with nitro
dx and tx
ACS (assume HA) ↓ barium swallow - corkscrew esophagus ↓ manometry - random contractions ↓ NO EGD
Tx: CCB, nitro
Infrequent, large caliber pieces of food get stuck in throat
dx and tx
“steak house dysphagia” - Schatzki Ring
dx
barium swallow - normal lumen with ring
↓
EGD with Bx = ring
tx lysis during EGD
female with dysphagia, iron deficiency anemia, webs….and eventually esophageal cancer
dx and tx
Esophageal webs and plummer-vinson syndrome
dx
barium - webs
↓
EGD screen for cancer
tx: EGD screen for cancer
warning: do NOT do an esophagectomy
Old man with halitosis, chokes while eating…regurgitates undigested food
Zenker’s diverticulum
dx
barium swallow - pouch
↓
EGD with Bx = visualization
tx surgical resection (endoscopic or open)
GERD, dysphagia, weight loss
stricture or cancer
barium swallow – symmetric for stricture, asymmetric for cancer (i.e. fungating mass)
EGD with bx – no cancer = stricture, cancer = cancer.
stricture = type IV GERD
↑ Pain with food
dx and tx
PUD: gastric location
EGD with bx, rule out h pylori and malignancy
Tx: PPI, stop EtOh, NSAIDs, smoking
↓ Pain with food
PUD: duodenal location
EGD with bx, rule out h pylori and malignancy
tx: PPI, stop EtOH, NSAIDs, smoking
Etiologies of PUD
H pylori: single ulcers NSAIDs: multiple ulcers Malignancy: heaped, necrotic Curling's: burns Cushings: steroids Gastrinoma
↑ or ↓ pain with food + other symptoms of indigestion
Dx and Tx
H. Pylori infection
Pt:
PUD + dyspepsia: 15%
Maltoma = 1%
Asx = 85%
dx: Urea breath test: initial Serology = test and treat (once) Stool antigen = for eradication EGD with bx = best (histology)
tx:
- clarithromycin
- amoxicillin
- PPI
Diarrhea, epigastric/abdominal pain. EGD with bx: big virulent ulcers refractory to treatment
dx and tx
Zollinger Ellison - gastrin secreting tumor
dx:
- Gastrin < 250 = normal
- Gastrin > 1600 = Gastrinoma
- (250–1600) = increased secretion stimulation
- CT scan
tx: resection
Burning CP, worse with recumbency and/or spicy food. Improved by sitting up and antacids
dx and tx
GERD
dx:
PPI + lifestyle modifications
If alarm symptoms –> EGD with bx
24 hr pH monitoring
tx: GERD: PPI Metaplasia: PPI Dysplasia: local ablation Adeno: resection
Hoarseness, coughing, stridor, nocturnal asthma
GERD, atypical
dx:
PPI + lifestyle modifications
If alarm symptoms –> EGD with bx
24 hr pH monitoring
tx: GERD: PPI Metaplasia: PPI Dysplasia: local ablation Adeno: resection
Chronic N/V, abdominal pain, peripheral neuropathy
dx and tx
Gastroparesis, idiopathic/diabetic
dx:
- nuclear emptying study
- above 60% @ 24 hrs
- below 10% @ 4 hrs
tx:
- avoid opiates
- blood sugar control
- prokinetic agents
- metoclopromide, erythromycin, domperidone. Low fiber diet.
Habitual marijuana smoker with cyclic N/V they treat with marijuana
tx
Cyclic vomiting syndrome
tx: stop THC