Treatments Flashcards

1
Q

Orotic aciduria tx

A

oral uridine

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2
Q

Pyruvate DH complex deficiency tx

A

ketogenic diet (Lys and Leu)

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3
Q

Fructose intolerance tx

A

decrease fructose and sucrose intake

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4
Q

Classic galactosemia tx

A

decrease galactose and lactose intake

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5
Q

Hyperammonemia tx

A

benzoate or phenylbutyrate and lactulose

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6
Q

PKU tx

A

increase tyrosine

decrease phenylalanine

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7
Q

Cystinuria tx

A

alkalinization of urine and good hydration

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8
Q

Diphtheria prevention

A

toxoid vaccine

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9
Q

Listeria tx

A

ampicillin

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10
Q

TB tx

A

RIPE

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11
Q

MAC prophylaxis

A

azithromycin

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12
Q

Leprosy tx

A

dapsone and rifampin

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13
Q

Neisseria tx

A

ceftriaxone

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14
Q

H. influenza tx/prophylaxis

A

tx=ceftriaxone

pro=rifampin

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15
Q

Legionella tx

A

macrolides or quinolone

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16
Q

Pseudomonas tx

A

aminoglycosides plus penicillin

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17
Q

H pylori tx

A

PPI, clarithromycin, amoxicillin or metronidazole

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18
Q

Lymes diseases tx

A

doxycycline or cefriaxone

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19
Q

Syphilis tx

A

penicillin G

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20
Q

Tx for Gardnerella vaginalis

A

metronidazole

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21
Q

Chlamydia tx

A

azithromycin or doxycycline

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22
Q

Dimorphic fungi tx

A

ketoconazole

Amphotericin B in pregnancy

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23
Q

Pneumocystis tx

A

TMP-SMX, dapsone

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24
Q

Cryptosporidium tx

A

nitazoxanide

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25
Q

Toxoplasmosis tx

A

sulfadiazine and pyrimethamine

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26
Q

T brucei tx

A

suramin for blood

melarsprol for CNS

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27
Q

Plasmodium tx

A

chloroquine/mefloquine/quinidine

primaquine for vivax and ovale

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28
Q

Babesia tx

A

atovaquone and azithromycin

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29
Q

T. cruzi tx

A

nifurtimox

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30
Q

Leishmania donovani tx

A

Na+ stibogluconate

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31
Q

Tx for nematodes (roundworms)

A

pyrantel pamoate/ivermectin

diethylcarbamazine for Loa loa and W. bancrofti

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32
Q

Tx for cestodes (tapeworms) and trematodes (flukes)

A

praziquantel

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33
Q

Tx fo anaerobes

A

clindamycin

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34
Q

Drug for gram (+) bugs

A

penicillins and vancomycin

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35
Q

Drug for gram (-) rods

A

aminoglycosides

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36
Q

Drug for atypical pneumonias

A

macrolides

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37
Q

Drug for bacterial meningitis

A

chloramphenicol

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38
Q

Drug for gram (-) rods of urinary/GI tracts

A

fluoroquinolones

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39
Q

Drug for protozoa/fungi

A

metronidazole

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40
Q

Anaphylaxis for TB

A

isoniazid

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41
Q

Drug for dermatophytoses

A

terbinafine

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42
Q

Tx for influenza

A

zanamivir and oseltamivir

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43
Q

Tx for RSV or Hep C

A

Ribavirin

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44
Q

Tx for HSV/VZV

A

acyclovir

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45
Q

Tx for CMV

A

ganciclovir

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46
Q

Tx for MS

A

beta-interferon

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47
Q

Tx for chronic granulomatous disease

A

gamma-interferon

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48
Q

Tx for Torsades

A

Mg2+ sulfate

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49
Q

Tx for dilated cardiomyopathy

A

ACEI’s, diuretics, heart transplant

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50
Q

Tx for hypertrophic cardiomyopathy

A

Beta blockers and CCB’s

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51
Q

Tx for CHF

A

ACEI’s, Beta blockers, spironolactone

hydralazine for sx

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52
Q

Tx for temporal cell arteritis

A

high dose corticosteroids

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53
Q

Tx for Takayasu’s arteritis

A

corticosteroids

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54
Q

Tx for Kawasaki disease

A

aspirin and IVIG

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55
Q

Tx for Buerger’s disease (arterial)

A

Smoking cessation

56
Q

Tx for microscopic polyangiitis/Wegener’s

A

corticosteroids or cyclophosphamide

57
Q

Tx for HTN in pregnancy

A

hydralazine

58
Q

Tx for renal insufficiency HTN

A

fenoldopam (D1 agonist)

59
Q

Tx for hyperthyroidism

A

methimazole/propylthiouracil

60
Q

Tx for primary aldosteronism

A

spironolactone

61
Q

Tx for pheochromocytoma (drug)

A

phenoxybenzamine

62
Q

Tx for acromegaly

A

somatostatin analogs (octreotide)

63
Q

Diabetes insipidus tx

A

desmopressin (neurogenic)

HCT/indomethacin/amiloride (nephrogenic)

64
Q

Tx for SIADH

A

conivaptan/tolvaptan

demeclocycline

65
Q

Tx for diabetic ketoacidosis

A

IV fluids/insulin
K+
Glc

66
Q

Tx for carcinoid syndrome

A

octreotide

67
Q

Tx for Crohn’s disease

A

azathiprine/MTX/corticosteroids/monoclonal Abs

68
Q

Tx for Ulcerative colitis

A

Sulfasalazine/6-MP/corticosteroids/colectomy

69
Q

Tx for Hirschsprung’s

A

colonic resection

70
Q

Tx for physiologic neonatal jaundice

A

phototherapy

71
Q

Tx for Crigler-Najjar type II

A

phenobarbital (induces CYP)

72
Q

Tx for Wilson’s disease

A

penicillamine

73
Q

Tx for hemochromatosis

A

deferoxamine/phlebotomy

74
Q

Tx for primary biliary cirrhosis

A

ursodeoxycholic acid

75
Q

Tx for lead poisoning

A

EDTA first line

Succimer in kids

76
Q

Tx for sideroblastic anemia

A

B6 (pyridoxine)

77
Q

Tx for hereditary spherocytosis

A

splenectomy

78
Q

Tx for paroxysmal nocturnal hemoglobinuria

A

eculizumab

79
Q

Sickle cell tx

A

hydroxyurea

80
Q

Tx for acute intermittent porphyria

A

Glucose and heme (inhibits ALA synthase)

81
Q

Tx for von Willibrand Disease

A

desmopressin (releases vWF from endothelium)

82
Q

Tx for hairy cell leukemia

A

cladribine

83
Q

Tx for CML M3

A

Vit A (all trans retinoic acid)

84
Q

Tx for CLL

A

imatinib

85
Q

Tx for childhood tumors

A

actinomycin D

86
Q

Tx for brain tumors

A

nitrosoureas (-ustines)

87
Q

Tx for breast cancer (type of Ab)

A

trastuzumab

88
Q

Tx for B cell neoplasms

A

rituximab (CD20 Ab)

89
Q

Ab for melanoma

A

vemurafenib (Ab for B-RAF)

90
Q

Tx for Rheumatoid arthritis

A

NSAIDS/glucocorticoids

MTX/sulfasalazine/TNF-alpha inhibitors

91
Q

Tx for gout

A

allopurinol/febuxostat

colchcine for acute

92
Q

Tx for sarcoidosis

A

steroids (anabolic cause you wanna get HUUUGGGEEE!!!!)

93
Q

Tx for MS

A

interferon-beta
natalizumab
steroids

94
Q

Tx for cluster headache

A

sumatriptan

95
Q

Tx for migraine

A

triptans

prophylaxis=propanolol/topiramate

96
Q

Tx for glaucoma emergency

A

pilocarpine

97
Q

Tx for absence seizures

A

ethosuximide

98
Q

Tx for tonic-clonic seizures

A

phenytoin/carbamazepine/valproic acid

99
Q

Tx for simple or complex seizures

A

carbamazepine

100
Q

Tx for myoclonic seizures

A

valproic acid

101
Q

Tx for malignant hyperthermia

A

dantrolene

102
Q

Drug txs for Parkinson’s (4 types)

A

bromocriptine/pramipexole/rpinirole (D2 agonist)
amantadine (increases DA release)
selegiline (MAOI-B)/entacapone (MAOI-A)
Benztropine (antimuscarinic)

103
Q

Tx for Huntington’s

A

tetrabenazine/reserpine (inhibit VMAT, decrease DA release)

haloperidol (D1 antagonists)

104
Q

Tx for Tourette’s

A

antipsychotics

105
Q

Separation anxiety tx

A

SSRI’s

106
Q

Tx for delirium

A

haloperidol

107
Q

Tx for atypical depression

A

MAOI’s or SSRI’s

108
Q

Tx for panic disorder

A

SSRI’s/venlafaxine/benzo’s

109
Q

Specific phobias tx

A

SSRI’s

110
Q

OCD tx

A

SSRI’s/clomipramine

111
Q

Post traumatic stress disorder tx

A

SSRI’s

112
Q

Generalized anxiety disorder

A

SSRI’s/SNRI’s

113
Q

Benzo OD tx

A

flumazenil

114
Q

Tx for cocaine intox

A

benozdiazepines

115
Q

Tx for delirium tremens

A

benzodiazepines

116
Q

Tx for ADHD

A

methylphenidate/amphetamines

117
Q

Tx for bipolar disorder

A

Li+/valproic acid/carbamazepine

118
Q

Tx for neuroleptic malignant syndrome

A

dantrolene/D2 agonists

119
Q

Tx for uric acid/cystine stones

A

alkalinization of urine

120
Q

Renal cell carcinoma tx

A

resection if localized

resistant to chemo/radiation

121
Q

Hydatiform mole tx

A

C&D with MTX

122
Q

Tx for pre-eclampsia

A

Mg2+ sulfate (prevent seizures)

123
Q

Tx for endometritis

A

gentamycin + clindamycin +/- ampicillin

124
Q

Tx for mendometriosis

A

lueprolide/danazol

contraceptives/NSAIDs

125
Q

Tx for adenomyosis

A

hysterectomy

126
Q

Tx for PCOD

A

wt loss/oral contraceptives

spironolactone/clomiphene

127
Q

Tx for BPH

A

terazosin/tamsulosin (alph1 antagonism)

finasteride (5alpha-reductase inhibition)

128
Q

Tx for methemoglobinemia

A

methylene blue

129
Q

Tx for cyanide poisoning

A

thiosulfate

130
Q

Tx for neonatal respiratory distress syndrome

A

maternal steroids

131
Q

Tx for sleep apnea

A

wt loss/CPAP

132
Q

Tx for pulmonary arterial HTN

A

bosentan (endothelin-1 antagonist)

133
Q

Tx for breast cancer in postmenopausal women

A

anastrozole (aromatase inhibitor)

134
Q

Tx for prostate carcinoma

A

flutamide (androgen antagonist)

135
Q

Tx for schizophrenia

A
5HT2a antagonists (2nd gen antipsychotics) for negative sx
D2 antagonists for positive sx
136
Q

Tx of sporothrix schenckii

A

oral KCl