Rheumatology

Question 1

Dx for SLE

Answer 1

anti dsDNA
anti Smith
decreased complement

Question 2

Asscs with HLA-B27

Answer 2

psoriatic arthritis
Reactive arthritis
Ankylosing spondylitis

Question 3

Tx for SLE

Answer 3

acute=corticosteroids
long term=hydroxychloroquine
cyclophosphamide for glomerular involvement

Question 4

Most common cause of death with SLE

Answer 4

renal failure

Question 5

Dx of scleroderma

Answer 5

anti-centromere for limitied form

anti-topoisomerase I for diffuse form

Question 6

Sx of antiphospholipid Ab syndrome

Answer 6

arterial and venous thrombi
thrombocytopenia
livedo reticularis

Question 7

Assc with Sjogren’s

Answer 7

non Hodgkin’s lymphoma

Question 8

Tx for sjogren’s

Answer 8

pilocarpine
cevimeline
both for salivation/tears

Question 9

Findings with Felty syndrome

Answer 9

neutropenia
rheumatoid arthritis
splenomegaly

Question 10

Dx of RA

Answer 10

anti-citrullinated peptide Abs
elevated ESR and CRP
increased RF

Question 11

Tx for RA

Answer 11

NSAIDs for pain control

DMARDs (MTX, leflunamide)

Question 12

Sx of dermatomyositis (5)

Answer 12

proximal muscle weakness
Gottron's papules on hands
Shawl sign
heliotrope rash on face
periungal erythema

Question 13

Assc with dermatomyositis

Answer 13

increased malignancy

Question 14

Dx of dermatomyositis/polymyositis

Answer 14

elevated CK
elevated LDH, aldolse, AST and ALT
anti-synthetase Abs (Anti Jo-1 Abs)

Question 15

Sx of polymyalgia rheumatica

Answer 15

hip and shoulder pain

Question 16

Asscs with reactive arthritis (5)

Answer 16

chlamydia
campylobacter
shigella
salmonella
yersinia

Question 17

Sx of psoriatic arthritis

Answer 17

gradual onset

asymmetric and polyarticular

Question 18

Asscs with temporal cell arteritis (2)

Answer 18

polymyalgia rheumatica

aortic aneurysm/aortic dissection

Question 19

Sx of Churg-Strauss syndrome (3)

Answer 19

eosinophilia
asthma/dyspnea
palpable purpura

Question 20

Sx of Wegener’s (4)

Answer 20

sinusitis
oral ulcers
hemoptysis
GN

Question 21

Assc with polyarteritis nodosa

Answer 21

Hep B

HIV

Question 22

Sx of polyarteritis nodosa

Answer 22

abd pain (bowel angina)
HTN
livedo reticularis

Question 23

Dx of polyarteritis nodosa

Answer 23

mesenteric angiography

Question 24

Sx of Behcets syndrome

Answer 24

recurrent genital/oral ulcers
uveitis
meningioencephalitis