Rheumatology Flashcards
Dx for SLE
anti dsDNA
anti Smith
decreased complement
Asscs with HLA-B27
psoriatic arthritis
Reactive arthritis
Ankylosing spondylitis
Tx for SLE
acute=corticosteroids
long term=hydroxychloroquine
cyclophosphamide for glomerular involvement
Most common cause of death with SLE
renal failure
Dx of scleroderma
anti-centromere for limitied form
anti-topoisomerase I for diffuse form
Sx of antiphospholipid Ab syndrome
arterial and venous thrombi
thrombocytopenia
livedo reticularis
Assc with Sjogren’s
non Hodgkin’s lymphoma
Tx for sjogren’s
pilocarpine
cevimeline
both for salivation/tears
Findings with Felty syndrome
neutropenia
rheumatoid arthritis
splenomegaly
Dx of RA
anti-citrullinated peptide Abs
elevated ESR and CRP
increased RF
Tx for RA
NSAIDs for pain control
DMARDs (MTX, leflunamide)
Sx of dermatomyositis (5)
proximal muscle weakness Gottron's papules on hands Shawl sign heliotrope rash on face periungal erythema
Assc with dermatomyositis
increased malignancy
Dx of dermatomyositis/polymyositis
elevated CK
elevated LDH, aldolse, AST and ALT
anti-synthetase Abs (Anti Jo-1 Abs)
Sx of polymyalgia rheumatica
hip and shoulder pain
Asscs with reactive arthritis (5)
chlamydia campylobacter shigella salmonella yersinia
Sx of psoriatic arthritis
gradual onset
asymmetric and polyarticular
Asscs with temporal cell arteritis (2)
polymyalgia rheumatica
aortic aneurysm/aortic dissection
Sx of Churg-Strauss syndrome (3)
eosinophilia
asthma/dyspnea
palpable purpura
Sx of Wegener’s (4)
sinusitis
oral ulcers
hemoptysis
GN
Assc with polyarteritis nodosa
Hep B
HIV
Sx of polyarteritis nodosa
abd pain (bowel angina) HTN livedo reticularis
Dx of polyarteritis nodosa
mesenteric angiography
Sx of Behcets syndrome
recurrent genital/oral ulcers
uveitis
meningioencephalitis
