Therapeutics 1 Flashcards
which AB are time dependent? Concentration dependent?
time = penicillin, TMPS
concentration = gentamycin
use AB for subsolar abscess?
no, just drain
*also, don’t use for Strangles w lymphadenopathy, diarrhea
TMPS [ONLY ORAL EQUINE LICENSED AB] -
bacteriocidal vs static?
+, -, anaerobe?
time vs concentration dependent?
bacteriocidal
+, -
time
Pencillin -
bacteriocidal vs static?
+, -, anaerobe?
time vs concentration dependent?
bacteriocidal
+, -, anaerobe
time
what’s important to remember about giving penicillin
if Depocillin IV ==> seizure/ataxia b/c of the procaine
procaine also has withdrawal time for racehorses
Aminoglycosides -
bacteriocidal vs static?
+, -, anaerobe?
time vs concentration dependent?
concentration
aminoglycoside complication?
nephrotoxicity
*be careful when giving w NSAIDs or to dehydrated
should you use Pen Strep in horses
no, inadequate dose of Penicillin and only gives SID
cephalosporins -
bacteriocidal vs static?
+, -, anaerobe?
time vs concentration dependent?
bactericidal
+, -, anaerobe
time
Tetracyclines -
bacteriocidal vs static?
+, -, anaerobe?
time vs concentration dependent?
either
+, -, anaerobe, intracellular
either
when to use tetracylcine first line
intracellular
Fluoroquinolones -
bacteriocidal vs static?
+, -, anaerobe?
time vs concentration dependent?
bacteriocidal
+, -
concentration
fluoroquinolone complication
nephrotoxic
when to use macrolides
Rhodococcus equi in foals
can metronidzaole be used in FPA?
no