MSK 5 Flashcards
OA is a dx of movable joints characteristzed by
loss and cartilage, formation of new bone
why get OA?
-defective cartilage (flawed matrix)
-cartilage too thin
-mechanical forces
why think about cartilage damage more like organ failure than muscle damage
once it happens, cannot go backwards
purpose of chondrocyte
maintain a balance between matrix degredation and repair
what happens to cartilage throughout OA
becomes spongey/thick – > thins and fissures
presentation of OA
-pain on flexion
-effusion (on high motion joints)
-lameness
radiographic changes for OA
osteophyte formation
joint space narrowing
bone lysis
bone sclerosis
how to manage OA
-regular farriery and exercise
-NSAID (PBZ)
-steroids intra-articularly
side effects of long term NSAIDs
colitis
GI ulcer
renal necrosis
which corticosteroids are used for OA
methylprednisolone
triamcinolone
complications of IA steroids
-laminitis?
-don’t pick up joint infections
-fractures
what does Hayluronan (HA) do
Maintains synovial haemostasis
Provides elasticity/lubrication
polyacrylamide gel
cross linked polymer.
adheres to joint capsule,
synovial hyperplasia
bisphosphonates for OA
potent bone analgesia
inhibit bone breakdown
not for under 4yo
side effect of bisphosphonate
bad for kidneys (don’t use w NSAIDs)
low grade colic (give w buscopan)
