Surgery Pre/Post Op and Emergencies/transplant Flashcards
Hep patient preop check?
ALWAYS CHECK Clotting factors and platelets if liver concern so they don’t bleed out
What if on warfarin before surgery?
Stop it 3-4 days before surgery, switch to heparin allow INR to normalize
Restart warfarin postop
Restart heparin 12 hr post op and continue until therapeutic
DVT proph?
Aspirin, clop, warfarin, LMWH
Postop fever timing?
Pneumonia UTI DVT Wound infection Drug
Pneumo: day 3 UTI: 3-5 days DVT: Anytime Wound infection: 5-8 Meds: Just remember
Sinusitis maybe
Atelectasis ehhh, not specif
Post op fever workup?
CXR, CBC, UA and culture, Blood culture, Sputum culture maybe, Exam legs, Doppler US
NO D DIMER (b/c all post op patients have high D dimer)
Clean wound is clean skin. Clean contaminated goes into GI or resp or vagina. What is contaminated?
Contaminated wound is perforation.
Dirty is established infection!
Delayed primary close is what?
Dirty wounds leaving open before closing
Gallstone illeus is what?
Bowel obstruction with gall stone!
Diverticulitis tx?
Metronidazole and fluoroquinolone or maybe IV meds if necessary
What is papaverine?
Drug for less arterial vasospasm (used for mesenteric ischemia)
What is second look laparatomy?
Check a day after resection of dead bowel moved
Chronic mesenteric ischemia?
intestinal angina. Sometimes hear bruit. Pain within 2 hours of eating
Bone marrow transplant indications?
Aplastic anemia
Induciton chemo
Heart transplant indications?
Congen defects, cardiomyopathy, severe CAD
Lung transplants indications?
COPD, alph1antitrypsin, primary pulmonary HTN, CF
Hyperacute rejection?
24 hours: ANTI DONOR ANTIBODIES. Untreatable
ABO
Acute rejection is what? TX?
6 days to a year
Anti donor T cell proliferation
Tx: STEROIDS
Chronic rejection is what?
More than a year after transplant. Can’t treat
Cyclosporine adverse reaction?
Nephrotoxic. Mannitol can help
Azathioprene is what?
Toxicity?
When can’t you use it?
Antirejection
Adverse reaction: Bone marrow suppression
METAB BY XANTHINE OXIDASE
SO NO ALLOPURINOL!
Tacrolimus
Nephrotoxic
What is muromonab?
Leukopenia
Mycophenalate causes what?
Used in lupus
Cause bone marrow suppression
Hydroxychloroquine used when? What does it cause?
Anti rejection and lupus
Visual disturbances