Psych Flashcards
Major Depression requirements for dx
2 weeks with 5 or more symptoms of SIGECAPS if anhedonia or depressed mood
Sleep, interest, guilt, energy,, concentration, appetite, psychomotor (leaden paralysis or antzy), suicide
True or false, hyperparathyroidism can cause depression?
Yes, think calcium and psychiatric overtones
Dopamine blockers canc ause depression
Like metaclopramide, prochlorperazine, haloperidol
Med used for viral hepatitis that causes depression?
Interferon alpha
Atypical depression is what?
Treatment?
Like Karly.
Responds to MAOi’s (though SSRI is first line)
Peripartum depression is up to 4 weeks later. Psychotic features can happen b/c of depression
oh!
Important to differntiate mood disorder secondary to pyschoses and schizoaffective
Persistent depressive disorder
2 years or longer without 2 months without symptoms.
Need depressed mood plus 2 SIGECAPS
Desvenlafaxine, duloxetine, milnacipran, venlafaxine are what?
SNRIs and dizziness, serotonin syndrome, SEX DYSFUNCITON!
Serotonin syndrome sx?
Mental status change, autonomic excitation, neuromuscular hyperactive, OCULAR CLONUS
Drugs that increase risk of serotonin. ESPECIALLY the antibiotic
SSRI, SNRI, MAOIs, St johns, tryptophan (precursur)
LINEZOLID
Tx of serotonin syndrome?
Discontinue
Supportive and vitals
Benzos for sedation
If temp above 41, PARALYZE and mechanically cool
If still agitated, use cyproheptadine
What is cyproheptadine used for?
Still agitated after bento given after serotonin syndrome
it is serotonin antagonist
Neuromalignant syndrome vs Serotonin syndrome?
NMS is gradula onset and rigidity wearas 5HT is hyperkinesis and clonus
both have autonomic instability, hyperthermia and muscle problems
Bupropion mechanism?
what is nice about it?
Bad about it? (contraindications)
weight loss, keeps awake, NO SEXUAL DYSFUNCTION
Lowers seizure threshold
Mirtazapine mechanism. Side effect?
Alpha 2 blocker, so more adrenergic.
Causes sedation and wt gain