HIV Flashcards
Acute phase HIV is what?
Like mono but higher fevers and mucosal ulcers
last a few weeks
Cryptosporidium tx?
Nitazoxonide (AIDs defining illness, it is from things that happened at NIGHT)
Wasting syndrom is what?
Losing body weight with HIV and CD4 low
Tx witth emgesterol and testosterone if both are low
ANTIRETROVIRAL therapy is best
Cocciodiomycocis in HVIV
Cough, fever, disseminated disease
Bilateral infiltrates on CXR with positive antibodies
Tx: fluconazole or ampho
AIDS dementia? Tx
Low CD4 with ataxia, intellectual decline
ANTIRETROVIRAL THERAPY IS TX
CAndida esophagitis is AIDS defining illness. Dx? Tx?
Very painful swallowing
Oral or IV fuc
Nystatin
Ampho
HIstoplasmosis tx?
Amphotericin B or fluconazol
What is concern about history of toxoplasmosis in low CD4?
Reactivation of it. Need prophylaxis
Pyramethine, leucovorin
HIV with focal neurologic symptoms think what?
Toxoplamsosis or LYMPHOMA!!!
What is progressive multifocal leukoencephalopathy?
PCR test on CSF does it
VIRAL DISEASE BUT NO GOOD TREATMENT
Cryptococcus stain?
India ink. Antigen studies usually used
Ampho and fluconazole
Cytomegalovirus concern in HIV?
RAPID VISUAL LOSS
Can cause esophagitis with painful ulcers!!!
Foscarnet or ganciclovir
Mycobacterium avid complex? MAC? Tx?
MACROLIDES for MAC
It is from blood cultures
HIV screening?
ELISA for HIV antibodies
Specific test for HIV?
western blot
Side effects of NRTIs?
Lipodystrophy
LACTIC ACIDOSIS CAN BE DEADLY
Abacavir bad side effect?
HYPERSENSITIVITY (can be deadly)
Zidovudine side effect?
Bone marrow suppression is always asked
Which are the NNRTIs? Major side effect?
They are the vir in the middle.. Inhibit reverse transcriptase
Rash is side effect
Efavirenz side effect?
NNRTI so RASH and
TERATOGENIC AND NEUROPSYCH SYMPTOMS
Protease inhibitors end in what?
NAVIR. Boosted with ritonavir
Block activation of virus
Atazanavir side effect?
HYPERBILIRUBINemia
Side effect of protease inhibitors
Navir cause METABOLIC issues and GI side effects
HAART basics?
2 NRTIs and one of the others
Screening for HIV in infant?
They will all be positive form mom’s antibodies
So the screening is for viral load
Prophylaxis in HIV? KNOW THIS!
CD4 less than 200
PCP TMPSMX
Toxoplasmosis TMPSMX
MAC Macrolide