Bone disease

Question 1

Male with osteoporosis?

Answer 1

Check testosterone

Question 2

Additional med you give if you give somebody steroids 3 months?

Answer 2

bisphosphonate to prevent osteoporosis

Question 3

Concern with raloxifene for osteoporosis tx?

Answer 3

Clotting

Question 4

What is teriparatide?

Answer 4

PTH analog can be used pulsatile fashion (Terry Acke has osteoporosis)

Question 5

Demosunab?

Answer 5

RANK L inhib for osteoporosis

Question 6

Osteopetrosis problem?

Answer 6

Ostoeclast dysfunciton

Question 7

Osteopetrosis history?

Answer 7

More fracture, nerve issues b/c compression. Anemia b/c less marrow cavities

Thickening of skull so hat doesn’t fit

Question 8

Paget disease of bone is what disorder?

Answer 8

overactive clasts and blasts

Usually asymptomatic

Hearing loss b/c nerve compression
Bigger hats
Kyphosis
Bowing of tibia

Question 9

BOWIN OF TIBIA?

Answer 9

Paget disease of bone

Question 10

Pagets alk phos, calcium and phos?

Answer 10

Alk phos is high, calcium and phosphate is normal

Question 11

Pagets tx?

Answer 11

usually no need for treatment, but bisphosphanates can be used

Question 12

Tx of osteogenesis imperfecta?

Answer 12

Activity restriction, bisphosphanates

Collagen 1 disorder

Question 13

Gout tx?

Answer 13

NSAIDs

Steroids can help

Colchicine (give it until diarrhea used to be how they did it)

Allopurinol
Probenecid inhibits urate resorption

Question 14

Joints pseudogout affects?

Answer 14

Knee or wrist positive rhomboid

Question 15

tx of psudogout?

Answer 15

NSAIDs

Colchicine

Question 16

Chondrocalcinosis is with what?

Answer 16

pseudogout

SAW IT WITH DESOUZA DURING THE SURGERY

Question 17

Dx of Paget?

Answer 17

Radionuclide bone scan