SUPERFICIAL MYCOSES - maam t (part 2) Flashcards
occur almost exclusively in debilitated patients whose normal defense mechanisms are impaired.
Opportunistic Systemic Mycoses
risk factors for opportunistic fungal infection
- Neutropenia <500 neutrophils/ml for more than 10 days
- Hematological malignancies
- Bone Marrow Transplantation
- Prolonged (>4 wks) treatment with corticosteroids
- Prolonged (>7 days) stays in intensive caree
- Chemotherapy
- HIV infection
most common opportunistic yeast infection in the world
Candidiasis
- similar to F. pedrosoi but with more compact conidial heads
- conidia are subglobose
Fonsecaea compactum
- conidiophores erect, dark, leaving conidia only on upper portion
- conidia elliptic, one-celled, produced sympodially
Rhinocladiella aquaspersa
- erect conidiophores bearing branched chains of one-celled brown blastoconidia
- conidium close to tip of conidiophore, termed “shield cell”
cladophialophora carrionii
infection of subcutaneous tissue arising at the site of incoulation
mycetoma
mycetoma caused by bacteria
Actinomycotic mycetomas
mycetoma caused by fungal agents
Eumycotic mycetoma
hyaline, septate, filamentous mold
Acremonium falciforme/Fusarium falciforme
madurella specie that grows best at 37 degree celsius with slower growth
madurella mycetomatis
madurella specie that grows best at 40 degree celsisus and only hyphae has been observed and the optimal temperature is 30 degree celsius
Madurella grisea
mycotic disease caused by darkly pigmented fungi
subcutaneous phaeohyphomycosis
conidia are borne from annelids
exophiala species
forms conidia at the tips of phialides
Exophiala dermatitidis
- delicate hyaline, septate hyphae
- arrange laterally along hyphae or in daisy-like cluster
mold (sporothrix schenkii)
- oval or elliptical in shape
- cigar-shaped forms
yeast (sporothrix schenkii)
fungal disease of the keratinized tissue of humans and other animals
dermatomycoses
dermatophytoses
symptoms of cutaneous disease
itching, scaling, ring-like patches, brittle, broken hairs, thick discolored nails
inhabit the skin and produce numerous conidia
Geophilic
adapted to live in animals; fewer conidia
zoophilic
adapted exclusively to human hosts; only few conidia
anthropophilic
tricophyton specieis
T. rubrum
T. tonsurans
T. schoenleinii
T. mentagrophytes
T. verrucosum
T. violaceum
common cause of food and nail infection
Trichophyton
Trichophyton colony
Mycelia - cream, brown, granular to wrinkled
Trichophyton microscopic features
microconidia - oval, pyriform; attached singly, some in clusters; hyaline septate hyphae
- white downy to pink granular
- yellow when colony is young; red when old culture
Tricophyton rubrum
Tricophyton rubrum microscopic feature
microconidia usually teardrop shaped
Tricophyton rubrum disease
Tinea pedis, Tinea coporis
- white, tan to yello or rust, suede-like to powdery
Tricophyton tonsurans
Tricophyton tonsurans microconidia
teardrop or club-shaped with flat bottoms
Tricophyton tonsurans disease
Ringworm
- smooth, white to creamy colony
- white
Tricophyton schoenleinii
Tricophyton schoenleinii microscopy
hyphae - favic chandeliers
Tricophyton schoenleinii disease
favus or tinea favosa
- white, granular and fluffy
- light-yellow periphery in younger cultures
Tricophyton mentagrophytes
Tricophyton mentagrophytes microscopy
many round to globose microconidia