Lymphoid Organ and Cells of Immune System

Question 1

Primary lymphoid organs includes

Answer 1

Bone Marrow and Thymus

Question 2

the site of B cells and T cell maturation.

Answer 2

Primary Lymphoid Organ: Bone Marrow and Thymus

Question 3

Secondary lymphoid organ includes

Answer 3

Lymph Nodes, Tonsils, Appendix, Spleen, Peyer’s Patchers

Question 4

It is the site of proliferation and differentiation of T cells and B cells.

Answer 4

Secondary lymphoid organ

Question 5

Trapping site of pathogens, Production of
antibodies and site of phagocytosis.

Answer 5

Secondary lymphoid organ

Question 6

Cells of immune system: innate immunity

Answer 6

Neutrophil
Eosinophil
Basophil
Mast Cell
Macrophage
Dendritic Cells

Question 7

Polymorphonuclear leukocytes; respond to bacterial infection.

Answer 7

Neutrophil

Question 8

Produce toxic proteins against certain parasites.

Answer 8

Eosinophil

Question 9

Responds to allergic and hypersensitivity reactions.

Answer 9

Basophil

Question 10

Tissue based basophil; binds with IgE.

Answer 10

Mast Cell

Question 11

Precursor of monocyte; cells that migrate to the tissue; APC’s or Antigen Presenting Cell

Answer 11

Macrophage

Question 12

Resemble the dendrites of nerve cells; APC’s

Answer 12

Dendritic cells

Question 13

Cells that responds to bacterial infection.

Answer 13

Neutrophil

Question 14

It is highly phagocytic and motile cells.

Answer 14

Neutrophil

Question 15

Neutrophil is active in the ______ stage of infection.

Answer 15

initial

Question 16

lobes of neutrophil

Answer 16

2 to 5 lobes

Question 17

It has a phagocytic effect and have the ability
to leave the blood.

Answer 17

Eosinophil

Question 18

eosinophil major role is to produce toxic proteins against parasites such as _______.

Answer 18

helminths

Question 19

It releases substances such as histamine, that are important in inflammation and allergic response.

Answer 19

BASOPHIL and MAST CELL

Question 20

Mast cells resembles _____ but larger
and more granules, it bind with ____.

Answer 20

basophils ; IgE

Question 21

It has a major role in phagocytosis and antigen
presenting cells.

Answer 21

Macrophage

Question 22

2 types of macrophage

Answer 22

Fixed
Wandering

Question 23

it is like a check post that will not allow the intruder to enter critical locations in the body.

Answer 23

Fixed Macrophage

Question 24

are roaming around connective tissue throughout the body.

Answer 24

Wandering Macrophage

Question 25

dendritic cells is believed to derived from _____

Answer 25

monocytes

Question 26

- Covered with long membranous extensions. - Phagocytize antigen and present it to helper T lymphocytes. - Most potent phagocytic cell in the tissue.

Answer 26

DENDRITIC CELLS

Question 27

It kills extracellular organisms only.

Answer 27

Phagocytosis

Question 28

stages of phagocytosis

Answer 28

1. Initiation Stage 2. Chemotaxis 3. Engulfment 4. Digestion 5. Excretion

Question 29

substances released by the cells

Answer 29

Cytokines

Question 30

cytokines includes

Answer 30

1. Interleukins 2. Interferon 3. Tumor Necrosis Factor 4. Chemokines 5. Betalysin 6. Complement

Question 31

an overall reaction of the body to injury or invasion by an infectious agent that is described by ________

Answer 31

Inflammation ; Aulus Cornelius Celsus

Question 32

functions of inflammation

Answer 32

- To destroy injurious agent. - To limit the effects on the body by confining or walling off injurious agent and its by products. - To repair or replace tissue damaged by the injurious agent or by its product.

Question 33

cardinal signs of inflammation

Answer 33

i. Rubor: Redness ii. Calor: Heat iii. Dolor: Pain iv. Tumor: Swelling v. Functio Laesa: Loss of Function

Question 34

STAGES OCCUR IN INFLAMMATION

Answer 34

1. Vascular Response 2. Cellular Response 3. Resolution and Repair

Question 35

Increased the blood supply and increased capillary permeability.

Answer 35

Vascular Response

Question 36

Migration of PMNs from the capillaries to the surrounding of tissues.

Answer 36

Cellular response

Question 37

Migration of macrophages to the injured sites.

Answer 37

Cellular response

Question 38

resolution and repair stage of inflammation is initiated by ________

Answer 38

fibroblast proliferation

Question 39

cells of immune system: adaptive immunity

Answer 39

T cells, B cells and Natural Killer Cells

Question 40

chief lymphocytes in blood and lymph.

Answer 40

T cells

Question 41

precursor cell in antibody production.

Answer 41

B cells

Question 42

it kills infected and malignant cells.

Answer 42

Natural Killer Cells

Question 43

Cells of Immune System: Adaptive Immunity T cells subsets

Answer 43

CD4 CD8

Question 44

a t-cell subset that is a Helper cells or Inducer cells

Answer 44

CD4

Question 45

a t-cell subset that is a Suppressor or Cytotoxic cells

Answer 45

CD8

Question 46

T cells development

Answer 46

1. Double Negative Thymocytes 2. Double Positive Thymocytes 3. Mature T cells 4. Activated T cells 5. Sensitized T cells

Question 47

B cells development

Answer 47

1. Pro B Cells 2. Pre B Cells 3. Immature Cells 4. Mature B Cells 5. Activated B Cells

Question 48

B cell development with successful rearrangement of heavy chain genes

Answer 48

Pro B Cells

Question 49

B cell development with synthesis of the heavy chain part of the antibody molecule and surrogate light chain.

Answer 49

Pre B Cells

Question 50

Immature cells in B cell development is distinguished by the appearance of complete _____ molecules on the cell surface.

Answer 50

IgM

Question 51

Completion of light chain rearrangements commits (in what B cell development?)

Answer 51

Immature Cells

Question 52

In mature B cells (B cells development), ___ and ___ is present on the surface.

Answer 52

IgM and IgD

Question 53

Activated B Cells exhibit identifying markers that include _____ which is found on both activated T cells and B cells and act as a receptor for ______.

Answer 53

CD25 ; interleukin 2

Question 54

antibody production

Answer 54

Plasma Cells